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使用三维打印聚乳酸模具定制聚甲基丙烯酸甲酯颅骨成形植入物:附2例说明性病例的技术笔记

Customized Polymethylmethacrylate Cranioplasty Implants Using 3-Dimensional Printed Polylactic Acid Molds: Technical Note with 2 Illustrative Cases.

作者信息

Abdel Hay Joe, Smayra Tarek, Moussa Ronald

机构信息

Department of Neurosurgery, Hôtel-Dieu de France Hospital, Saint-Joseph University, Beirut, Lebanon.

Department of Radiology, Hôtel-Dieu de France Hospital, Saint-Joseph University, Beirut, Lebanon.

出版信息

World Neurosurg. 2017 Sep;105:971-979.e1. doi: 10.1016/j.wneu.2017.05.007. Epub 2017 May 11.

DOI:10.1016/j.wneu.2017.05.007
PMID:28502686
Abstract

OBJECTIVES

Prefabricated customized cranioplasty implants are anatomically more accurate than manually shaped acrylic implants but remain costly. The authors describe a new cost-effective technique of producing customized polymethylmethacrylate (PMMA) cranioplasty implants with the use of prefabricated 3-dimensional (3D) printed molds.

METHODS

The first patient had a left frontal cranial defect after a craniotomy for a glial tumor. A 3D image of his skull was obtained from axial 0.6-mm computed tomography (CT) scan images. The image of the implant was generated by a digital subtraction mirror-imaging process using the normal side of his cranium as a model. The second patient had a bifrontal defect after the resection of an infected customized polyetheretherketone implant. A 3D image of the infected implant was directly obtained from an axial 0.6-mm CT scan before discarding it. The images were then used to produce for each patient a mold of the external surface of the cranium using a low-cost polylactic acid 3D printer. Intraoperatively, each mold was put in a sterile bag and then used to cast a customized PMMA implant subsequently trimmed before fixation.

RESULTS

Both patients had excellent cosmetic results and underwent postoperative CT scans that showed excellent restoration of the symmetrical contours of the cranium. No neurologic or infectious complications occurred over a 6-month follow-up for either patient.

CONCLUSIONS

Making customized PMMA cranioplasty implants via 3D printed polylactic acid molds is a cost-effective technique for delayed reconstruction of various cranial defects.

摘要

目的

预制定制的颅骨成形植入物在解剖学上比手工塑形的丙烯酸植入物更精确,但成本仍然很高。作者描述了一种使用预制三维(3D)打印模具生产定制聚甲基丙烯酸甲酯(PMMA)颅骨成形植入物的新的经济有效技术。

方法

首例患者因胶质细胞瘤开颅术后出现左侧额部颅骨缺损。通过0.6毫米轴向计算机断层扫描(CT)扫描图像获得其颅骨的3D图像。以其颅骨正常侧为模型,通过数字减法镜像成像过程生成植入物图像。第二例患者在切除感染的定制聚醚醚酮植入物后出现双额部缺损。在丢弃感染的植入物之前,通过0.6毫米轴向CT扫描直接获得其3D图像。然后使用低成本的聚乳酸3D打印机,根据这些图像为每位患者制作颅骨外表面的模具。术中,将每个模具放入无菌袋中,随后用于浇铸定制的PMMA植入物,在固定前进行修剪。

结果

两名患者均获得了出色的美容效果,术后CT扫描显示颅骨对称轮廓得到了出色的恢复。两名患者在6个月的随访中均未出现神经或感染并发症。

结论

通过3D打印聚乳酸模具制作定制的PMMA颅骨成形植入物是一种用于各种颅骨缺损延迟重建的经济有效技术。

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