Schilling Thomas M, Bossert Magdalena, Weisbrod Matthias, Aschenbrenner Steffen
Sektion für Klinische Psychologie und Neuropsychologie, SRH Klinikum Karlsbad-Langensteinbach GmbH, Guttmanstraße 1, 76307, Karlsbad, Deutschland.
Abteilung für Psychiatrie und Psychotherapie, SRH Klinikum Karlsbad-Langensteinbach, Guttmanstraße 1, 76307, Karlsbad, Deutschland.
Nervenarzt. 2021 Mar;92(3):277-288. doi: 10.1007/s00115-021-01074-4. Epub 2021 Mar 1.
Cognitive impairments are frequent in patients suffering from major depressive disorders. They are among the first symptoms, often persist independently of improvement even after remission of the affective symptoms and are an important predictor of psychosocial functioning. In the clinical practice it is mandatory to ask about subjective complaints of the patient as well as to assess the cognitive abilities with the help of a standardized neuropsychological test battery. Cognitive remediation, selective serotonin reuptake inhibitors (SSRI) and vortioxetine as well as repetitive transcranial magnetic stimulation have proven their effectiveness as treatment options.
认知障碍在重度抑郁症患者中很常见。它们是最早出现的症状之一，即使在情感症状缓解后，也常常独立于病情改善而持续存在，并且是心理社会功能的重要预测指标。在临床实践中，必须询问患者的主观主诉，并借助标准化的神经心理测试组来评估认知能力。认知康复、选择性5-羟色胺再摄取抑制剂（SSRI）、伏硫西汀以及重复经颅磁刺激已被证明作为治疗方案是有效的。
