Haring B, Weismann D
Medizinische Klinik und Poliklinik I, Schwerpunkt Internistische Notfall- und Intensivmedizin, Universitätsklinikum Würzburg.
Dtsch Med Wochenschr. 2021 Mar;146(5):331-334. doi: 10.1055/a-1239-5316. Epub 2021 Mar 1.
Taxines are the active, poisonous constituents in yew plants (Taxus spp.) and can result in life-threatening cardiac toxicity. Rapid elimination of yew plant material and administration of active charcoal can limit absorption of toxins. Treatment is confined to supportive care. Therapeutic interventions such as utilization of digoxin immune fab, hemodialysis and temporary cardiac pacing may be utilized. Extracorporeal life support should be considered for severe cases.
紫杉碱是红豆杉属植物中的活性有毒成分,可导致危及生命的心脏毒性。迅速清除红豆杉植物物质并给予活性炭可限制毒素吸收。治疗仅限于支持性护理。可采用地高辛免疫Fab、血液透析和临时心脏起搏等治疗干预措施。严重病例应考虑体外生命支持。