Kalmansohn R B, Kalmansohn R W, Markham C H, Schiff D L
UCLA Medical Center.
Angiology. 1988 Apr;39(4):371-4. doi: 10.1177/000331978803900407.
Diabetic neuropathy includes a heterogenous group of neuropathic syndromes associated with diabetes mellitus. One form of diabetic neuropathy is distal symmetric polyneuropathy, which is characterized at a late stage by intractable pain. This pain is generally refractory to present modalities of therapy except for narcotics. Pentoxifylline offers a new approach to therapy, reducing the blood viscosity and improving perfusion of ischemic microcirculation. A case report will be presented of intractable painful peripheral neuropathy responding dramatically to pentoxifylline therapy.
糖尿病性神经病变包括一组与糖尿病相关的异质性神经病变综合征。糖尿病性神经病变的一种形式是远端对称性多发性神经病变，其晚期特征为顽固性疼痛。除了麻醉药外，这种疼痛通常对目前的治疗方式无效。己酮可可碱提供了一种新的治疗方法，可降低血液粘度并改善缺血性微循环的灌注。将介绍一例顽固性疼痛性周围神经病变对己酮可可碱治疗有显著反应的病例报告。
