Yadav Divya, Kumar Rakesh
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Diagnostic Nuclear Medicine Division, Department of Nuclear Medicine, AIIMS, Ansari nagar, New Delhi 110029, India.
PET Clin. 2021 Apr;16(2):177-189. doi: 10.1016/j.cpet.2020.12.007.
2-[18F]-fluoro-2-deoxyglucose (FDG) is the most commonly used radiotracer and provides valuable information about glucose metabolism. With the advent of newer receptor-based tracers in the management of hormonally active malignancies, the focus has been shifted from FDG. These tracers might be more specific than FDG because they target specific hormone receptors. But because FDG is widely available, this review discusses what information still can be harnessed from this workhorse of molecular imaging. The personalized implementation of FDG imaging in undifferentiated malignancies will help in characterization of tumor and may aid in patient management.
2-[18F]-氟-2-脱氧葡萄糖（FDG）是最常用的放射性示踪剂，可提供有关葡萄糖代谢的有价值信息。随着基于受体的新型示踪剂在激素活性恶性肿瘤管理中的出现，关注点已从FDG转移。这些示踪剂可能比FDG更具特异性，因为它们靶向特定的激素受体。但由于FDG广泛可得，本综述讨论了从这种分子成像的主力军中仍可获取哪些信息。在未分化恶性肿瘤中个性化实施FDG成像将有助于肿瘤特征的描述，并可能有助于患者管理。
