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疼痛恐惧、焦虑或抑郁患者全髋关节和膝关节置换术后的结果。

Postoperative Outcomes Following Total Hip and Knee Arthroplasty in Patients with Pain Catastrophizing, Anxiety, or Depression.

机构信息

Division of Orthopaedic Surgery, McMaster University, Hamilton, Ontario, Canada; Complex Care and Othopaedics Program, Hamilton Health Sciences Juravinski Hospital, Hamilton, Ontario, Canada.

Division of Orthopaedic Surgery, McMaster University, Hamilton, Ontario, Canada.

出版信息

J Arthroplasty. 2021 Jun;36(6):1908-1914. doi: 10.1016/j.arth.2021.02.018. Epub 2021 Feb 11.

Abstract

BACKGROUND

The relationship among pain catastrophizing, emotional disorders, and total joint arthroplasty (TJA) outcomes is an emerging area of study. The purpose of this study is to examine the association of these factors with 1-year postoperative pain and functional outcomes.

METHODS

A prospective cohort study of preoperative TJA patients using the Pain Catastrophizing Scale and Hospital Anxiety and Depression Scale (HADS-A/HADS-D) was conducted. Postoperative outcomes included Visual Analog Scale (VAS) pain, Oxford, Harris Hip (HHS) and Knee Society (KSS) scores. Median regression was used to assess the pattern of relationship among preoperative clinically relevant catastrophizing (CRC) pain, abnormal HADS, and 1-year postoperative outcomes.

RESULTS

We recruited 463 TJA patients, all of which completed 1-year follow-up. At 1 year, CRC-rumination (adjusted median difference 1; 95% confidence interval [CI] 0.31-1.69, P = .005) and abnormal HADS-A (adjusted median difference 1; 95% CI 0.36-1.64, P = .002) were predictors of VAS pain, CRC magnification a predictor of HHS/KSS (adjusted median difference 1.3; 95% CI 5.23-0.11, P = .041), and abnormal HADS-A a predictor of Oxford (adjusted median difference 3.68; 95% CI 1.38-5.99, P = .002). CRC patients demonstrated inferior VAS pain (P = .001), Oxford (P < .0001), and HHS/KSS (P = .025). Abnormal HADS patients demonstrated inferior postoperative VAS (HADS-A, P = .025; HADS-D, P = .030) and Oxford (HADS-A, P = .001; HADS-D, P = .030). However, patients with CRC experienced significant improvement in VAS, Oxford, and HHS/KSS (P < .05) from preoperative to 1 year. Similarly, patients with abnormal HADS showed significant improvement in VAS pain and HHS/KSS (P < .05).

CONCLUSION

TJA patients who are anxious, depressed, or pain catastrophizing have inferior preoperative and postoperative pain and function. However, as compared to their preoperative status, clinically significant improvement can be expected following hip/knee arthroplasty.

摘要

背景

疼痛灾难化、情绪障碍与全关节置换术(TJA)结果之间的关系是一个新兴的研究领域。本研究的目的是检验这些因素与术后 1 年疼痛和功能结果的关系。

方法

对使用疼痛灾难化量表和医院焦虑抑郁量表(HADS-A/HADS-D)的术前 TJA 患者进行前瞻性队列研究。术后结果包括视觉模拟评分(VAS)疼痛、牛津大学、髋关节(HHS)和膝关节协会(KSS)评分。中位数回归用于评估术前临床相关灾难化(CRC)疼痛、异常 HADS 与术后 1 年结果之间的关系模式。

结果

我们招募了 463 名 TJA 患者,他们均完成了 1 年随访。1 年后,CRC 反刍(调整后中位数差异 1;95%置信区间 [CI] 0.31-1.69,P =.005)和异常 HADS-A(调整后中位数差异 1;95% CI 0.36-1.64,P =.002)是 VAS 疼痛的预测因素,CRC 放大是 HHS/KSS 的预测因素(调整后中位数差异 1.3;95% CI 5.23-0.11,P =.041),异常 HADS-A 是牛津大学的预测因素(调整后中位数差异 3.68;95% CI 1.38-5.99,P =.002)。CRC 患者表现出较差的 VAS 疼痛(P =.001)、牛津大学(P <.0001)和 HHS/KSS(P =.025)。异常 HADS 患者术后 VAS(HADS-A,P =.025;HADS-D,P =.030)和牛津大学(HADS-A,P =.001;HADS-D,P =.030)较差。然而,与术前相比,CRC 患者的 VAS、牛津大学和 HHS/KSS 有显著改善(P <.05)。同样,异常 HADS 患者的 VAS 疼痛和 HHS/KSS 有显著改善(P <.05)。

结论

焦虑、抑郁或疼痛灾难化的 TJA 患者术前和术后疼痛和功能均较差。然而,与术前状态相比,髋关节/膝关节置换术后可预期显著改善。

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