Department of Primary Care and Public Health, Imperial College London, London, UK.
Cardiology, West Middlesex University Hospital, London, UK.
Open Heart. 2021 Feb;8(1). doi: 10.1136/openhrt-2020-001558.
Atrial fibrillation (AF) is the most common arrhythmia. Undiagnosed and poorly managed AF increases risk of stroke. The Hounslow AF quality improvement (QI) initiative was associated with improved quality of care for patients with AF through increased detection of AF and appropriate anticoagulation. This study aimed to evaluate whether there has been a change in stroke and bleeding rates in the Hounslow population following the QI initiative.
Using hospital admissions data from January 2011 to August 2018, interrupted time series analysis was performed to investigate the changes in standardised rates of admission with stroke and bleeding, following the start of the QI initiative in October 2014.
There was a 17% decrease in the rate of admission with stroke as primary diagnosis (incidence rate ratio (IRR) 0.83; 95% CI 0.712 to 0.963; p<0.014). There was an even larger yet not statistically significant decrease in admission with stroke as primary diagnosis and AF as secondary diagnosis (IRR 0.75; 95% CI 0.550 to 1.025; p<0.071). No significant changes were observed in bleeding admissions. For each outcome, an additional regression model including both the level change and an interaction term for slope change was created. In all cases, the slope change was small and not statistically significant.
Reduction in stroke admissions may be associated with the AF QI initiative. However, the immediate level change and non-significant slope change suggests a lack of effect of the intervention over time and that the decrease observed may be attributable to other events.
心房颤动(AF)是最常见的心律失常。未确诊和管理不善的 AF 会增加中风的风险。豪恩斯洛 AF 质量改进(QI)计划通过增加 AF 的检出率和适当的抗凝治疗,改善了 AF 患者的护理质量。本研究旨在评估 QI 计划实施后,豪恩斯洛人群中风和出血率是否发生变化。
使用 2011 年 1 月至 2018 年 8 月的住院数据,采用中断时间序列分析,调查 2014 年 10 月 QI 计划启动后,以中风和出血为主要诊断的住院标准化率的变化。
以中风为主要诊断的住院率下降了 17%(发病率比(IRR)0.83;95%CI 0.712 至 0.963;p<0.014)。以中风为主要诊断且 AF 为次要诊断的住院率下降更为显著,但无统计学意义(IRR 0.75;95%CI 0.550 至 1.025;p<0.071)。出血住院率无显著变化。对于每个结果,都创建了一个包含水平变化和斜率变化交互项的额外回归模型。在所有情况下,斜率变化都很小且无统计学意义。
中风住院人数的减少可能与 AF QI 计划有关。然而,即时的水平变化和非显著的斜率变化表明干预措施在一段时间内没有效果,并且观察到的减少可能归因于其他事件。