Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA.
Section of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.
J Perinatol. 2021 Oct;41(10):2408-2416. doi: 10.1038/s41372-021-01003-y. Epub 2021 Mar 1.
This study evaluates differences in child healthcare utilization by maternal fertility status in the first four years of life.
The retrospective cohort evaluated Massachusetts (MA) live born infants using data linked from clinical assisted reproductive technology (ART) data, birth certificates, and hospital discharge records. Hospital records of infants born 2004-2017 to mothers of fertile (no infertility treatments or indicators of infertility), unassisted subfertile (UF, indicators of infertility but no fertility treatment), medically assisted reproduction (MAR, non-ART assistance with reproduction) and ART treatment were studied. Adjusted relative risk (aRR) was calculated using multivariable log binomial regression models.
We included 339,426 singleton live-born infants discharged from birth hospitalization. Compared to children born to fertile mothers, those born to UF, MAR and ART-treated mothers were more likely to have hospital-based care (aRR 1.06-1.21) in their first 4 years.
Maternal subfertility with and without treatment was associated with small increases in child healthcare utilization.
本研究评估了在生命的头四年中，母亲生育状况对儿童保健利用的差异。
本回顾性队列研究使用临床辅助生殖技术（ART）数据、出生证明和医院出院记录，对马萨诸塞州（MA）活产婴儿进行了评估。研究了 2004-2017 年间母亲生育能力正常（无不孕治疗或不孕指标）、未经辅助的轻度不孕（UF，有不孕指标但未经不孕治疗）、医学辅助生殖（MAR，非 ART 辅助生殖）和 ART 治疗的婴儿的医院记录。使用多变量对数二项式回归模型计算调整后的相对风险（aRR）。
我们纳入了 339426 名单胎活产婴儿，他们从出生住院中出院。与生育能力正常的母亲所生的婴儿相比，UF、MAR 和接受 ART 治疗的母亲所生的婴儿在头 4 年更有可能接受基于医院的护理（aRR 1.06-1.21）。
有和没有治疗的母体轻度不孕与儿童保健利用率的微小增加有关。
