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老年人中的致命 COVID-19：先天免疫记忆帮助最需要的人。

Deadly COVID-19 among the elderly: Innate immune memory helping those most in need.

机构信息

Department of Cardiology I - Coronary and Peripheral Vascular Disease, Heart Failure, University Hospital Münster, Münster, Germany.

Institutes of Molecular Genetics of the Czech Academy of Sciences, Prague, Czechia.

出版信息

Med. 2021 Apr 9;2(4):378-383. doi: 10.1016/j.medj.2021.02.004. Epub 2021 Feb 24.

DOI:10.1016/j.medj.2021.02.004
PMID:33649749
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7903897/
Abstract

Age is a key risk factor associated with the severity of symptoms caused by SARS-CoV-2, and there is an urgent need to reduce COVID-19 morbidity and mortality in elderly individuals. We discuss evidence suggesting that trained immunity elicited by BCG vaccination may improve immune responses and can serve as a strategy to combat COVID-19 in this population.

摘要

年龄是与 SARS-CoV-2 引起的症状严重程度相关的关键风险因素，迫切需要降低老年人群 COVID-19 的发病率和死亡率。我们讨论了一些证据，表明 BCG 疫苗接种引起的训练免疫可能改善免疫反应，并可作为该人群对抗 COVID-19 的一种策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5528/7903897/d2001a1d0fa3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5528/7903897/2c06e056929d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5528/7903897/d2001a1d0fa3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5528/7903897/2c06e056929d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5528/7903897/d2001a1d0fa3/gr2.jpg

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