Department of Global Health and Population, Harvard TH Chan School of Public Health, Boston, MA, USA.
Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.
Eur J Epidemiol. 2021 Feb;36(2):197-211. doi: 10.1007/s10654-021-00728-6. Epub 2021 Mar 1.
With the development of multiple effective vaccines, reducing the global morbidity and mortality of COVID-19 will depend on the distribution and acceptance of COVID-19 vaccination. Estimates of global vaccine acceptance among pregnant women and mothers of young children are yet unknown. An understanding of the challenges and correlates to vaccine acceptance will aid the acceleration of vaccine administration within these populations. Acceptance of COVID-19 vaccination among pregnant women and mothers of children younger than 18-years-old, as well as potential predictors, were assessed through an online survey, administered by Pregistry between October 28 and November 18, 2020. 17,871 total survey responses from 16 countries were obtained. Given a 90% COVID-19 vaccine efficacy, 52.0% of pregnant women (n = 2747/5282) and 73.4% of non-pregnant women (n = 9214/12,562) indicated an intention to receive the vaccine. 69.2% of women (n = 11,800/17,054), both pregnant and non-pregnant, indicated an intention to vaccinate their children. Vaccine acceptance was generally highest in India, the Philippines, and all sampled countries in Latin America; it was lowest in Russia, the United States and Australia. The strongest predictors of vaccine acceptance included confidence in vaccine safety or effectiveness, worrying about COVID-19, belief in the importance of vaccines to their own country, compliance to mask guidelines, trust of public health agencies/health science, as well as attitudes towards routine vaccines. COVID-19 vaccine acceptance and its predictors among women vary globally. Vaccination campaigns for women and children should be specific for each country in order to attain the largest impact.
随着多种有效疫苗的发展，降低 COVID-19 的全球发病率和死亡率将取决于 COVID-19 疫苗的分发和接受程度。目前尚不清楚全球孕妇和幼儿母亲对疫苗的接受程度。了解疫苗接受的挑战和相关因素将有助于加速这些人群接种疫苗。
通过由 Pregistry 在 2020 年 10 月 28 日至 11 月 18 日期间进行的在线调查，评估了孕妇和 18 岁以下儿童的母亲对 COVID-19 疫苗的接受程度以及潜在的预测因素。共获得来自 16 个国家的 17871 份总调查回复。考虑到 COVID-19 疫苗的 90%有效率，52.0%的孕妇（n=2747/5282）和 73.4%的非孕妇（n=9214/12562）表示打算接种疫苗。69.2%的女性（n=11800/17054），包括孕妇和非孕妇，表示打算为孩子接种疫苗。
疫苗接受度在印度、菲律宾和拉丁美洲所有抽样国家中最高；在俄罗斯、美国和澳大利亚中最低。疫苗接受度的最强预测因素包括对疫苗安全性或有效性的信心、对 COVID-19 的担忧、对疫苗对本国重要性的信念、遵守口罩指南、对公共卫生机构/卫生科学的信任，以及对常规疫苗的态度。
全球范围内，女性对 COVID-19 疫苗的接受程度及其预测因素存在差异。针对妇女和儿童的疫苗接种运动应针对每个国家的具体情况，以实现最大影响。
