Reymann F, Ravnborg L, Schou G, Engholm G, Osterlind A, Thestrup-Pedersen K
Department of Dermatology, Finsen Institute, Copenhagen, Denmark.
Arch Dermatol. 1988 May;124(5):677-9.
In a retrospective study of 581 patients with a diagnosis of Bowen's disease (BD) treated over a 40-year period, we traced patient records to identify later diagnoses of nonskin cancer. Fifty patients had nonskin cancer, as against an expected number of 40, but this difference was not significant. The lack of association was equally true for BD on sun-exposed and non-sun-exposed skin. Our findings support the view that BD is not a skin marker for internal malignant disease.
在一项对581例诊断为鲍恩病（BD）且治疗时间超过40年的患者的回顾性研究中，我们追踪患者记录以确定后来非皮肤癌的诊断情况。50例患者患有非皮肤癌，而预期数量为40例，但这种差异并不显著。对于暴露于阳光下和未暴露于阳光下皮肤的BD患者，缺乏关联的情况同样存在。我们的研究结果支持以下观点：BD并非是内部恶性疾病的皮肤标志物。
