Hösli M, Overesch G, Willi B, Heim D, Hatt J-M
Klinik für Zoo-, Heim- und Wildtiere, Vetsuisse-Fakultät, Universität Zürich.
Institut für Veterinärbakteriologie, Vetsuisse-Fakultät, Universität Bern.
Schweiz Arch Tierheilkd. 2021 Mar;163(3):227-237. doi: 10.17236/sat00295.
Monitoring programs and guidelines on the use of antibiotics and antibiotic resistance in human and veterinary medicine have been developed worldwide to promote the prudent use of antibiotics in recent years. However, such information on the use of antibiotics in exotic pets is absent. This fact must be taken into account, since the number of exotic pet patients is constantly increasing and the administration of antibiotics is particular challenging due to the diversity of species and the differences in physiology. The present study reports the results of a survey of frequently used antibiotics and the criteria of antibiotic usage in exotic pets (rabbits, rodents, birds and reptiles) among Swiss veterinarians. These data should form the basis for the development of antibiotic usage guidelines in exotic pets. A total of 61 veterinarians returned the questionnaire. The most important decision-making criteria for antibiotic treatment and antibiotic selection were clinical symptoms (55/59, 93% for antibiotic treatment and 40/59, 68% for antibiotic selection), experience (41/59, 69% and 36/59, 61%, respectively) and textbooks (39/59, 66% and 40/59, 68%). The most important decision-making criteria for dosage and duration of therapy were textbooks (59/59, 100%) and experience (31/59, 53%). The use of a microbial culture was used as a decision criterion for both antibiotic treatment and antibiotic selection by 39% of the participants, sensitivity testing was chosen as a decision criterion by 37% for antibiotic treatment and by 46% for antibiotic selection. Fluoroquinolones were used most frequently, 46/56 (82% of the participants) for rabbits, 49/57 (86%) for rodents, 36/37 (97%) for reptiles and 38/46 (83%) for birds. The vast majority of veterinarians (57/58, 98%) would consult a guide for the use of antibiotics. The frequent use of critical antibiotics in exotic pets underscores the need for a guide to the prudent use of antibiotics. The positive influence of such guidelines has already been proven in dogs and cats.
近年来,世界各地已制定了人类和兽医学中抗生素使用及抗生素耐药性的监测计划和指南,以促进抗生素的谨慎使用。然而,关于外来宠物抗生素使用的此类信息却不存在。必须考虑到这一事实,因为外来宠物患者的数量在不断增加,而且由于物种的多样性和生理差异,抗生素的使用尤其具有挑战性。本研究报告了瑞士兽医对外来宠物(兔子、啮齿动物、鸟类和爬行动物)常用抗生素及抗生素使用标准的调查结果。这些数据应成为制定外来宠物抗生素使用指南的基础。共有61名兽医回复了问卷。抗生素治疗和抗生素选择的最重要决策标准是临床症状(抗生素治疗为55/59,93%;抗生素选择为40/59,68%)、经验(分别为41/59,69%和36/59,61%)和教科书(39/59,66%和40/59,68%)。治疗剂量和疗程的最重要决策标准是教科书(59/59,100%)和经验(31/59,53%)。39%的参与者将微生物培养用作抗生素治疗和抗生素选择的决策标准,37%的参与者选择敏感性测试作为抗生素治疗的决策标准,46%的参与者选择其作为抗生素选择的决策标准。氟喹诺酮类药物使用最为频繁,兔子为46/56(82%的参与者),啮齿动物为49/57(86%),爬行动物为36/37(97%),鸟类为38/46(83%)。绝大多数兽医(57/58,98%)会查阅抗生素使用指南。外来宠物中关键抗生素的频繁使用凸显了制定抗生素谨慎使用指南的必要性。此类指南的积极影响已在犬猫中得到证实。