Tulchinsky M, Krasnow S H
Medical Service, Washington Veterans Administration Medical Center, Washington, DC 20422.
Arch Intern Med. 1988 May;148(5):1217-9.
A patient presented with syncope, and a diagnosis of carotid sinus syndrome was established. Further evaluation revealed a large nasopharyngeal carcinoma invading the left petrous bone. There were no cervical metastases. The tumor partially regressed with radiation therapy, and there was complete resolution of the carotid sinus syndrome, but the patient died three months later of metastatic disease. Autopsy confirmed petrous bone involvement by the mass but no cervical metastatic disease. This is the first reported case (to our knowledge) of malignancy-associated carotid sinus syndrome attributable to a primary nasopharyngeal carcinoma. The literature on malignancy-associated carotid sinus syndrome is reviewed, with emphasis on pathophysiology and treatment.
一名患者出现晕厥，诊断为颈动脉窦综合征。进一步评估发现巨大鼻咽癌侵犯左侧岩骨。无颈部转移。肿瘤经放射治疗后部分消退，颈动脉窦综合征完全缓解，但患者3个月后死于转移性疾病。尸检证实肿块累及岩骨，但无颈部转移性疾病。据我们所知，这是首例由原发性鼻咽癌引起的恶性肿瘤相关性颈动脉窦综合征的报道病例。本文回顾了恶性肿瘤相关性颈动脉窦综合征的文献，重点关注病理生理学和治疗。
