Zhang Si-Cheng, Lin Mao-Qing, Zhang Li-Wei, Lin Xue-Qin, Luo Man-Qing, Lin Kai-Yang, Guo Yan-Song
Department of Cardiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, China.
Fujian Provincial Key Laboratory of Cardiovascular Disease, Fujian Cardiovascular Institute, Fujian Provincial Center for Geriatrics, Fujian Provincial Clinical Research Center for Severe Acute Cardiovascular Diseases, Fuzhou, China.
Front Cardiovasc Med. 2022 Jan 10;8:796653. doi: 10.3389/fcvm.2021.796653. eCollection 2021.
Carotid sinus syndrome is a principal cause of syncope in the elderly. Syncope, associated with carotid sinus syndrome which is secondary to metastasis of advanced nasopharyngeal carcinoma, rarely occurs. The current study reported a 66-year-old woman, who presented with a history of frequent and recurrent syncope as the initial symptom, and was eventually diagnosed with advanced nasopharyngeal carcinoma. The positron emission tomography scan demonstrated a diagnosis of advanced nasopharyngeal carcinoma with involvement in carotid sheath space, and nasopharyngeal biopsy revealed non-keratinized nasopharyngeal carcinoma. After diagnosis and treatment, the patient had no recurrence of syncope. In summary, our case study suggests that great importance should be attached to potential intrinsic causes of syncope especially in the case of nasopharyngeal carcinoma, as it is an insidious malignancy which needs to be precisely identified.
颈动脉窦综合征是老年人晕厥的主要原因。与晚期鼻咽癌转移继发的颈动脉窦综合征相关的晕厥很少发生。本研究报告了一名66岁女性，她以频繁反复晕厥史为首发症状，最终被诊断为晚期鼻咽癌。正电子发射断层扫描显示诊断为晚期鼻咽癌，累及颈动脉鞘间隙，鼻咽活检显示为非角化性鼻咽癌。诊断和治疗后，患者晕厥未复发。总之，我们的病例研究表明，应高度重视晕厥的潜在内在原因，尤其是在鼻咽癌病例中，因为它是一种需要精确识别的隐匿性恶性肿瘤。
