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90 岁及以上的患者在髋部骨折后一年的死亡率增加。

Patients aged ninety years and older are exposed to increased risk of one-year mortality after hip fractures.

机构信息

Department of Orthopedics and Traumatology, Hospital Universitario de La Samaritana, Carrera 8 # 0 - 29 Sur, 110411, Bogotá, D.C., Colombia.

出版信息

Eur J Orthop Surg Traumatol. 2021 Oct;31(7):1501-1506. doi: 10.1007/s00590-021-02918-0. Epub 2021 Mar 2.

DOI:10.1007/s00590-021-02918-0
PMID:33651223
Abstract

BACKGROUND

The increase in the population over 90 years old suggests an expected surge in the number of extreme elderly patients sustaining hip fractures.

OBJECTIVE

The aim of this study is to identify factors associated with 1-year mortality and determine the conditions that are associated with an unfavorable survival outcome in nonagenarians.

DESIGN

Cross-sectional study SUBJECTS: Nonagenarian patients presenting with hip fractures between 2013 and 2018.

METHODS

Bivariate and multivariate analyses were performed to identify variables associated with mortality, and a survival analysis was conducted to determine whether the Charlson Comorbidity Index (CCI) is associated with mortality.

RESULTS

A total of 127 patients, with a mean age of 92.84 years was assessed, identifying 1-year mortality rate in 53.5% of patients. According to the bivariate analysis, requirement of postoperative vasopressor support, transfusion, decompensated heart failure and general anesthesia were associated with a higher probability of 1-year mortality after surgery. Body mass index, health status, dementia or CCI ≥ 3 were not associated with mortality. Similarly, the Kaplan-Meier survival analysis showed no difference in mortality rate of patients with CCI ≥ 3 (p = 0.282).

CONCLUSION

Patients older than 90 years with hip fractures have higher mortality rates per year than younger patients. Some associations were found, but more studies are needed to reach final conclusions, which could help identify higher-risk patients and be able to implement additional measures.

摘要

背景

90 岁以上人口的增加表明,髋部骨折的超高龄患者数量预计将大幅增加。

目的

本研究旨在确定与 1 年死亡率相关的因素,并确定与 90 岁以上患者生存不良结局相关的情况。

设计

横断面研究

受试者

2013 年至 2018 年间发生髋部骨折的 90 岁以上患者。

方法

进行了单变量和多变量分析,以确定与死亡率相关的变量,并进行了生存分析,以确定 Charlson 合并症指数(CCI)是否与死亡率相关。

结果

共评估了 127 例平均年龄为 92.84 岁的患者,其中 53.5%的患者在 1 年内死亡。根据单变量分析,术后需要血管加压支持、输血、失代偿性心力衰竭和全身麻醉与手术后 1 年死亡率较高相关。体质指数、健康状况、痴呆或 CCI≥3 与死亡率无关。同样,Kaplan-Meier 生存分析显示 CCI≥3 的患者死亡率无差异(p=0.282)。

结论

髋部骨折的 90 岁以上患者每年的死亡率高于年轻患者。虽然发现了一些相关性,但还需要更多的研究来得出最终结论,这有助于识别高风险患者并采取额外的措施。

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Pre-operative factors associated with increased mortality in elderly patients with a hip fracture: A cohort study in a developing country.老年髋部骨折患者死亡率增加的术前相关因素:一项发展中国家的队列研究。
Injury. 2018 Jun;49(6):1162-1168. doi: 10.1016/j.injury.2018.04.007. Epub 2018 Apr 13.
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Predictive factors of hospital stay, mortality and functional recovery after surgery for hip fracture in elderly patients.
日本80岁及以上人群中枢神经系统药物与股骨骨折风险的关联:一项病例交叉研究。
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Efficacy of surgical intervention over conservative management in intertrochanteric fractures among nonagenarians and centenarians: a prospective cohort study.手术干预与保守治疗在 90 岁及以上高龄股骨转子间骨折患者中的疗效比较:一项前瞻性队列研究。
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Ultra-old patients and long-term survival after hip fracture: a real-world assessment.超高龄患者与髋部骨折后的长期生存:一项真实世界评估
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Risk factors and prognosis of postoperative delirium in nonagenarians with hip fracture.90 岁以上髋部骨折患者术后谵妄的风险因素和预后。
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