胰腺脂肪变性与代谢综合征和超声弹性成像检测到的胰腺硬度均相关。
Pancreatic Steatosis Is Associated with Both Metabolic Syndrome and Pancreatic Stiffness Detected by Ultrasound Elastography.
机构信息
Department of Gastroenterology, Faculty of Medicine, Mersin University, Mersin Üniversitesi Çiftlikköy Kampüsü Tıp Fakültesi Hastanesi 2. Kat Gastroenteroloji Endoskopi Ünitesi Yenişehir, Mersin, Turkey.
出版信息
Dig Dis Sci. 2022 Jan;67(1):293-304. doi: 10.1007/s10620-021-06844-3. Epub 2021 Mar 2.
INTRODUCTION
There is increasing evidence that pancreatic steatosis (PS) is associated with metabolic syndrome (MS). However, it is not known whether it is associated with PS grade and pancreatic stiffness, or not. We aimed to evaluate the relationship between PS and its grade detected by transabdominal ultrasound, and pancreatic stiffness determined by two-dimensional shearwave elastography (2D-SWE), whether it has clinical significance and its relationship with MS.
METHODS
Patients with and without PS were evaluated prospectively.
RESULTS
Patients with PS had higher odds ratio for MS (OR 5.49). Also, ultrasonographic grade of PS was associated with MS parameters and hepatosteatosis. Pancreatic SWE value was significantly higher in PS group and positively correlated with PS grade, liver fat, MS, number of MS criteria.
DISCUSSION/CONCLUSION: PS and its grade were associated with MS. In this first comprehensive PS-SWE study, we found that pancreas stiffness increased in the presence of PS, in correlation with PS grade and MS.
简介
越来越多的证据表明，胰腺脂肪变性（PS）与代谢综合征（MS）有关。然而，目前尚不清楚它是否与 PS 分级和胰腺硬度有关。我们旨在评估经腹部超声检测到的 PS 及其分级与二维剪切波弹性成像（2D-SWE）确定的胰腺硬度之间的关系，评估其是否具有临床意义及其与 MS 的关系。
方法
前瞻性评估有和无 PS 的患者。
结果
PS 患者发生 MS 的优势比更高（OR 5.49）。此外，PS 的超声分级与 MS 参数和肝脂肪变性相关。PS 组的胰腺 SWE 值明显较高，且与 PS 分级、肝脂肪、MS、MS 标准数量呈正相关。
讨论/结论：PS 及其分级与 MS 有关。在这项关于 PS-SWE 的首次综合研究中，我们发现 PS 存在时胰腺硬度增加，与 PS 分级和 MS 相关。
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