尿液游离 DNA 中的突变分析：结直肠癌中的 KRAS 基因
Mutational Analysis in Urinary Cell-Free DNA: KRAS in Colorectal Cancer.
机构信息
Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST S.r.l., Meldola, Italy.
出版信息
Methods Mol Biol. 2021;2292:23-33. doi: 10.1007/978-1-0716-1354-2_3.
PMID:33651349
Abstract
Urinary cell-free DNA offers an important noninvasive source of material for genomic testing also for nonurological tumors. Its clinical utility in monitoring tumor evolution and treatment failure is promising. Here we describe a method to detect cancer mutations into urine from patients affected by colorectal cancer.
摘要
尿液游离 DNA 为非泌尿系统肿瘤的基因组检测提供了一个重要的非侵入性材料来源。它在监测肿瘤演变和治疗失败方面的临床应用具有广阔的前景。在这里，我们描述了一种从患有结直肠癌的患者尿液中检测癌症突变的方法。
Zotero 插件