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[淋巴瘤样肉芽肿病:3例病例的病理解剖学研究并文献复习及鉴别诊断]

[Lymphomatoid granulomatosis: pathologoanatomical study of three cases with a review of the literature and differential diagnosis].

作者信息

Pavlovskaia A I, Aĭkimbaev K S

出版信息

Arkh Patol. 1988;50(1):24-31.

PMID:3365135
Abstract

Evidence obtained at pathological investigation concerns 3 cases of lymphomatoid granulomatosis. The disease pertains to lymphoproliferative affections and is of rare occurrence. In addition to common involvement of the lungs, liver, kidneys, spleen, adrenals, etc., there was an advanced lymph node and brain lesion with abundant atypical cells in the infiltrate in the first and third case, respectively. The diagnosis rested on autopsy findings in 1 case and was intravital, established upon morphological examination of intraoperative specimens in 2 cases. Samples obtained at bronchoscopy are not fit for verification of the diagnosis in view of profound necrotic and necrobiotic processes in lymphomatoid granulomatosis.

摘要

病理检查获得的证据涉及3例淋巴瘤样肉芽肿病。该疾病属于淋巴增殖性疾病,较为罕见。除了常见的肺部、肝脏、肾脏、脾脏、肾上腺等受累外,第一例和第三例分别出现了晚期淋巴结病变和脑病变,浸润中有大量非典型细胞。1例诊断基于尸检结果,2例基于术中标本的形态学检查在生前确诊。鉴于淋巴瘤样肉芽肿病存在严重的坏死和渐进性坏死过程,支气管镜检查所取样本不适合用于诊断验证。

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