Ermakova N G
Arkh Patol. 1988;50(1):59-64.
Leukocytic chemotaxis was evaluated in 43 patients with diffuse purulent peritonitis. It was found out that time course changes in chemotactic activity of leukocytes have a phasic pattern: it was reduced in an early postoperative period, there is a tendency to enhancement of cellular spontaneous and target migration 3-6 days after operation and onwards, maximal response to chemotactic stimulus on day 7-14 after operative intervention. Postoperative serum factors show a diverse influence on leukocytic chemotaxis. Correlation observed between chemotaxic activity and postoperative developments allows the author to propose an assessment of leukocytic chemotaxis in patients with diffuse purulent peritonitis on follow-up to diagnose early complications and to control immunocorrective therapy administered.
对43例弥漫性化脓性腹膜炎患者的白细胞趋化性进行了评估。结果发现，白细胞趋化活性的时间进程变化呈阶段性模式：术后早期降低，术后3 - 6天及之后细胞自发迁移和靶向迁移有增强趋势，术后干预后第7 - 14天对趋化刺激的反应最大。术后血清因子对白细胞趋化性有多种影响。趋化活性与术后病情发展之间的相关性使作者能够提出对弥漫性化脓性腹膜炎患者进行白细胞趋化性评估，以便在随访中诊断早期并发症并控制所给予的免疫纠正治疗。
