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自适应心脏圆锥束计算机断层扫描(ACROBEAT):开发下一代心脏圆锥束 CT 成像技术。

Adaptive CaRdiac cOne BEAm computed Tomography (ACROBEAT): Developing the next generation of cardiac cone beam CT imaging.

机构信息

Faculty of Medicine and Health, ACRF Image X Institute, University of Sydney, Sydney, NSW, 2006, Australia.

Innovation, Advanced Therapies, Siemens Healthcare, Forchheim, 91301, Germany.

出版信息

Med Phys. 2021 May;48(5):2543-2552. doi: 10.1002/mp.14811. Epub 2021 Mar 23.

Abstract

PURPOSE

An important factor when considering the use of interventional cone beam computed tomography (CBCT) imaging during cardiac procedures is the trade-off between imaging dose and image quality. Accordingly, Adaptive CaRdiac cOne BEAm computed Tomography (ACROBEAT) presents an alternative acquisition method, adapting the gantry velocity and projection rate of CBCT imaging systems in accordance with a patient's electrocardiogram (ECG) signal in real-time. The aim of this study was to experimentally investigate that ACROBEAT acquisitions deliver improved image quality compared to conventional cardiac CBCT imaging protocols with fewer projections acquired.

METHODS

The Siemens ARTIS pheno (Siemens Healthcare, GmbH, Germany), a robotic CBCT C-arm system, was used to compare ACROBEAT with a commercially available conventional cardiac imaging protocol that utilizes multisweep retrospective ECG-gated acquisition. For ACROBEAT, real-time control of the gantry position was enabled through the Siemens Test Automation Control system. ACROBEAT and conventional image acquisitions of the CIRS Dynamic Cardiac Phantom were performed, using five patient-measured ECG traces. The traces had average heart rates of 56, 64, 76, 86, and 100 bpm. The total number of acquired projections was compared between the ACROBEAT and conventional acquisition methods. The image quality was assessed via the contrast-to-noise ratio (CNR), structural similarity index (SSIM), and root-mean square error (RMSE).

RESULTS

Compared to the conventional protocol, ACROBEAT reduced the total number of projections acquired by 90%. The visual image quality provided by the ACROBEAT acquisitions, across all traces, matched or improved compared to conventional acquisition and was independent of the patient's heart rate. Across all traces, ACROBEAT averaged 1.4 times increase in the CNR, a 23% increase in the SSIM and a 29% decrease in the RMSE compared to conventional and was independent of the patient's heart rate.

CONCLUSION

Adaptive patient imaging is feasible on a clinical robotic CBCT system, delivering higher quality images while reducing the number of projections acquired by 90% compared to conventional cardiac imaging protocols.

摘要

目的

在考虑心脏介入程序中使用锥形束计算机断层扫描(CBCT)成像时,一个重要的因素是在成像剂量和图像质量之间进行权衡。因此,自适应心脏锥形束 CT(ACROBEAT)提出了一种替代采集方法,根据患者的心电图(ECG)信号实时调整 CBCT 成像系统的旋转架速度和投影率。本研究的目的是实验性地研究与使用较少投影采集的传统心脏 CBCT 成像协议相比,ACROBEAT 采集可提供更高质量的图像。

方法

使用西门子 ARTIS pheno(西门子医疗有限公司,德国)机器人 CBCT C 臂系统,将 ACROBEAT 与利用多扫回顾性 ECG 门控采集的商业上可用的传统心脏成像协议进行比较。对于 ACROBEAT,通过西门子测试自动化控制系统实现了对旋转架位置的实时控制。使用五个患者测量的 ECG 迹线对 CIRS 动态心脏体模进行 ACROBEAT 和传统图像采集。迹线的平均心率分别为 56、64、76、86 和 100 bpm。比较了 ACROBEAT 和传统采集方法的采集投影总数。通过对比噪声比(CNR)、结构相似性指数(SSIM)和均方根误差(RMSE)评估图像质量。

结果

与传统协议相比,ACROBEAT 减少了 90%的采集投影总数。ACROBEAT 采集的所有迹线的视觉图像质量均与传统采集相当或更好,且与患者的心率无关。在所有迹线中,ACROBEAT 的 CNR 平均提高了 1.4 倍,SSIM 提高了 23%,RMSE 降低了 29%,与患者的心率无关。

结论

在临床机器人 CBCT 系统上实现了自适应患者成像,与传统心脏成像协议相比,可在减少 90%采集投影总数的情况下提供更高质量的图像。

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