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Reporting of financial conflicts of interest by Canadian clinical practice guideline producers: a descriptive study.报告加拿大临床实践指南制定者的财务利益冲突:描述性研究。
CMAJ. 2020 Jun 8;192(23):E617-E625. doi: 10.1503/cmaj.191737.
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Interactions between physicians and the pharmaceutical industry generally and sales representatives specifically and their association with physicians' attitudes and prescribing habits: a systematic review.医生与制药行业(总体而言)以及销售代表(具体而言)之间的互动及其与医生态度和处方习惯的关联:一项系统综述。
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Industry sponsorship and research outcome.行业赞助与研究成果。
Cochrane Database Syst Rev. 2017 Feb 16;2(2):MR000033. doi: 10.1002/14651858.MR000033.pub3.
4
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Res Integr Peer Rev. 2016;1. doi: 10.1186/s41073-016-0006-7. Epub 2016 May 3.
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Economic evaluation of vaccines in Canada: A systematic review.加拿大疫苗的经济评估:一项系统综述。
Hum Vaccin Immunother. 2016 May 3;12(5):1257-64. doi: 10.1080/21645515.2015.1137405. Epub 2016 Feb 18.
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Data fraud in clinical trials.临床试验中的数据欺诈。
Clin Investig (Lond). 2015;5(2):161-173. doi: 10.4155/cli.14.116.
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The ethics of sharing preliminary research findings during public health emergencies: a case study from the 2009 influenza pandemic.公共卫生突发事件中分享初步研究结果的伦理问题:以 2009 年流感大流行为例。
Euro Surveill. 2014 Jun 19;19(24):20831. doi: 10.2807/1560-7917.es2014.19.24.20831.
8
Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: a systematic review of published literature, 2007-2012.从全球视角理解疫苗犹豫和疫苗接种:对 2007-2012 年已发表文献的系统综述。
Vaccine. 2014 Apr 17;32(19):2150-9. doi: 10.1016/j.vaccine.2014.01.081. Epub 2014 Mar 2.
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Critical opportunities for public health law: a call for action.公共卫生法的关键机遇:行动呼吁。
Am J Public Health. 2013 Nov;103(11):1979-88. doi: 10.2105/AJPH.2013.301281. Epub 2013 Sep 12.
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Immunogenicity of 2 doses of HPV vaccine in younger adolescents vs 3 doses in young women: a randomized clinical trial.两剂 HPV 疫苗在青少年中的免疫原性与三剂 HPV 疫苗在年轻女性中的免疫原性比较:一项随机临床试验。
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“利益冲突”是一个用词不当的说法吗?管理免疫研究和评估中的利益。

Is 'conflict of interest' a Misnomer? Managing interests in immunization research and evaluation.

机构信息

Department of Obstetrics and Gynecology, Université de Montréal, Montréal, Quebec, Canada.

Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada.

出版信息

Hum Vaccin Immunother. 2022 Dec 31;18(1):1879580. doi: 10.1080/21645515.2021.1879580. Epub 2021 Mar 2.

DOI:10.1080/21645515.2021.1879580
PMID:33651972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8920130/
Abstract

Potential conflicts of interest in vaccine research can lead to negative consequences that undermine public trust and thereby put communities at risk. However, collaborations that may give rise to potential conflicts between interests can also greatly facilitate appropriate, scientifically robust, and timely vaccine development, implementation, and evaluation. At present, policies regarding the management of potential conflicts between interests are not ideal. To optimally manage interests in vaccine research, we recommend acknowledging all forms of interests and treating them all as relevant, developing appropriate collaborations, referring to all "conflicts of interest" simply as "interests" or "declarations," and promoting transparency through developing consistent reporting mechanisms.

摘要

疫苗研究中的潜在利益冲突可能会导致负面后果,破坏公众信任,从而使社区面临风险。然而,可能引发利益冲突的合作也可以极大地促进适当、科学有力和及时的疫苗研发、实施和评估。目前,关于管理潜在利益冲突的政策并不理想。为了在疫苗研究中实现利益的最佳管理,我们建议承认所有形式的利益,并将其全部视为相关利益,发展适当的合作关系,将所有“利益冲突”简单地称为“利益”或“声明”,并通过开发一致的报告机制来提高透明度。