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来自非流行地区旋毛虫病的临床和实验室特征。

Clinical and laboratory profile of trichinellosis from a non-endemic country.

机构信息

Department of Medical Parasitology, PGIMER, Chandigarh, India.

Department of Paediatrics, PGIMER, Chandigarh, India.

出版信息

Indian J Med Microbiol. 2021 Apr;39(2):235-239. doi: 10.1016/j.ijmmb.2021.02.004. Epub 2021 Feb 27.

DOI:10.1016/j.ijmmb.2021.02.004
PMID:33652039
Abstract

Trichinellosis is a zoonotic parasitic infection caused by nematodes of the genus Trichinella. Humans mostly get infected by eating raw/under-cooked pork. In India, it has been reported mostly as sporadic cases especially from North Eastern and Eastern part of country. In this study, we retrospectively analyzed the socio-demographic pattern, clinical presentation, laboratory profile and treatment response in Trichinella-infected patients visiting our tertiary care center which mainly caters to patients from North India. For this retrospective laboratory-based analysis, patients diagnosed on the basis of positive anti-Trichinella IgG antibodies between 1 June 2008, and 31 May 2019 were included. A total of 11 positive trichinellosis cases were detected, of whom majority were children who presented with history of fever, gastrointestinal symptoms, myalgia, eosinophilia along with hepatomegaly and pulmonary manifestations. No CNS involvement was seen in any of the patients although it is commonly associated with Trichinella infection. All patients recovered uneventfully after antihelminthic treatment.

摘要

旋毛虫病是一种由旋毛线虫属的线虫引起的人畜共患寄生虫感染。人类主要通过食用生的/未煮熟的猪肉而感染。在印度,它主要以散发病例的形式报告,特别是来自东北部和东部地区。在这项研究中,我们回顾性分析了在我们的三级保健中心就诊的旋毛虫感染患者的社会人口统计学模式、临床表现、实验室特征和治疗反应,该中心主要为来自印度北部的患者提供服务。这项基于实验室的回顾性分析纳入了 2008 年 6 月 1 日至 2019 年 5 月 31 日期间基于阳性抗旋毛虫 IgG 抗体诊断的患者。共检测到 11 例阳性旋毛虫病病例,其中大多数为儿童,他们有发热、胃肠道症状、肌痛、嗜酸性粒细胞增多症以及肝肿大和肺部表现。虽然旋毛虫感染通常与中枢神经系统受累有关,但在任何患者中均未观察到中枢神经系统受累。所有患者在驱虫治疗后均顺利康复。

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