Neuropsychology Research Unit, School of Psychology, The University of Queensland, St Lucia, Brisbane, Australia.
Taub Institute, Columbia University Medical Center, New York, New York.
Cogn Behav Neurol. 2021 Mar 3;34(1):38-52. doi: 10.1097/WNN.0000000000000261.
Verbal adynamia is characterized by markedly reduced spontaneous speech that is not attributable to a core language deficit such as impaired naming, reading, repetition, or comprehension. In some cases, verbal adynamia is severe enough to be considered dynamic aphasia. We report the case of a 40-year-old, left-handed, male native English speaker who presented with partial rhombencephalosynapsis, corpus callosum dysgenesis, and a language profile that is consistent with verbal adynamia, or subclinical dynamic aphasia, possibly underpinned by difficulties selecting and generating ideas for expression. This case is only the second investigation of dynamic aphasia in an individual with a congenital brain malformation. It is also the first detailed neuropsychological report of an adult with partial rhombencephalosynapsis and corpus callosum dysgenesis, and the only known case of superior intellectual abilities in this context.
言语无力症的特点是自发性言语明显减少，但并非归因于核心语言缺陷，如命名、阅读、重复或理解受损。在某些情况下，言语无力症严重到足以被视为动力性失语症。我们报告了一例 40 岁的左利手男性英语母语者，他表现出部分菱形脑回融合、胼胝体发育不良，以及与言语无力症或亚临床动力性失语症一致的语言特征，可能是由于在选择和生成表达想法方面存在困难。该病例是对先天性脑畸形个体中动力性失语症的第二次调查，也是首例关于部分菱形脑回融合和胼胝体发育不良的成人详细神经心理学报告，也是该背景下唯一已知的具有较高智力能力的病例。
