Kose Eiji, Endo Hidetatsu, Hori Hiroko, Hosono Shingo, Kawamura Chiaki, Kodama Yuta, Yamazaki Takashi, Yasuno Nobuhiro
Department of Pharmacy, Teikyo University School of Medicine University Hospital, 2-11-1 Kaga, Itabashi-ku, Tokyo, 173-8606, Japan.
Department of Pharmacy, Ogaki Tokushukai Hospital, 6-85-1 Hayashi-chou, Ogaki, Gifu, 503-0015, Japan.
J Pharm Health Care Sci. 2021 Mar 3;7(1):11. doi: 10.1186/s40780-021-00194-y.
Various factors are related to self-management of medication. However, few reports comprehensively examine the factors related to patients, medication levels, and other factors related to the recuperative environment, such as family support. The aim of this study was to investigate factors affecting the continuation of medication self-management among hospitalized older adults receiving convalescent rehabilitation.
We conducted a retrospective observational study with 274 consecutive patients newly admitted to the convalescent rehabilitation wards at a single hospital in Japan between January 2017 and May 2018. Participants who were assessed for their ability to take their medication using the Japanese Regimen Adherence Capacity Tests, were deemed to be self-manageable, and were able to successfully continue to self-manage their medication from admission to discharge were categorized as the "continuation group," and those who were not able to continue were categorized as the "non-continuation group." We analyzed the groups' demographic data, laboratory data, and Functional Independence Measure. The primary outcome was the continuation of medication self-management from admission to discharge.
After enrollment, 134 patients (median age 82 years; 62.7% women) were included in the final analysis. Some 60.4% of eligible patients were able to maintain medication self-management during their hospitalization. The multiple logistic regression analysis for the continuation of medication self-management during hospitalization after adjusting for confounding factors revealed that pharmacist medication instructions were independently and positively correlated with successful continuation of medication self-management (odds ratio: 1.378; 95% confidence interval 1.085-1.831; p = 0.0076).
Successful continuation of medication self-management is associated with pharmacist medication instructions among hospitalized older adults undergoing rehabilitation.
The Ethics Committee's registration number is "TGE01216-066".
多种因素与药物自我管理相关。然而，很少有报告全面研究与患者、用药水平以及诸如家庭支持等与康复环境相关的其他因素。本研究的目的是调查影响接受康复治疗的住院老年患者持续进行药物自我管理的因素。
我们进行了一项回顾性观察研究，研究对象为2017年1月至2018年5月期间日本一家医院康复病房连续收治的274例新入院患者。使用日本用药依从能力测试评估其服药能力、被认为具备自我管理能力且从入院到出院能够成功持续进行药物自我管理的参与者被归类为“持续组”，而未能持续进行自我管理的参与者被归类为“非持续组”。我们分析了两组的人口统计学数据、实验室数据和功能独立性测量结果。主要结局是从入院到出院持续进行药物自我管理。
入组后，134例患者（中位年龄82岁；62.7%为女性）纳入最终分析。约60.4%的符合条件患者在住院期间能够维持药物自我管理。在调整混杂因素后对住院期间药物自我管理持续情况进行的多因素logistic回归分析显示，药剂师的用药指导与药物自我管理的成功持续独立正相关（比值比：1.378；95%置信区间1.085 - 1.831；p = 0.0076）。
在接受康复治疗的住院老年患者中，药物自我管理的成功持续与药剂师的用药指导相关。
伦理委员会注册号为“TGE01216 - 066”。
