伴有血清学指标静止的系统性红斑狼疮多器官发作
Systemic lupus erythematosus multiorgan flare with quiescent serologic markers.
作者信息
Gile Jennifer Jane, Sara Jaskanwal Deep Singh, Mueller Michael R
机构信息
Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA.
出版信息
BMJ Case Rep. 2021 Mar 2;14(3):e239048. doi: 10.1136/bcr-2020-239048.
Abstract
Systemic lupus erythematosus (SLE) can affect almost every organ with differing degrees of severity. Typically, SLE activity is associated with hypocomplimentaemia and elevated double-stranded DNA (dsDNA) levels. We describe a case of a severe multiorgan lupus flare including lupus cerebritis, autoimmune haemolytic anaemia, lupus nephritis and lupus myopericarditis with normal complement and dsDNA levels. This highlights the importance of understanding the heterogeneous nature of SLE flares.
摘要
系统性红斑狼疮（SLE）可累及几乎每个器官，严重程度各不相同。通常，SLE活动与补体降低和双链DNA（dsDNA）水平升高有关。我们描述了一例严重的多器官狼疮发作病例，包括狼疮性脑病、自身免疫性溶血性贫血、狼疮性肾炎和狼疮性心肌心包炎，而补体和dsDNA水平正常。这突出了理解SLE发作异质性的重要性。
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