Reed R G
Medical Research Institute, Mary Imogene Bassett Hospital, Cooperstown, NY 13326.
Biochim Biophys Acta. 1988 May 12;965(2-3):114-7. doi: 10.1016/0304-4165(88)90045-1.
An albumin variant, isolated from the plasma of a patient with bisalbuminemia, was compared with albumin A from the same patient for binding of long-chain fatty acids and bilirubin. No differences in binding of [14C]palmitate, cis-parinaric acid or bilirubin could be detected for the variant form. These results suggest that the region adjacent to residue 365 is unlikely to be part of a major binding site for any of these ligands.
从双白蛋白血症患者血浆中分离出的一种白蛋白变体，与该患者的白蛋白A进行了长链脂肪酸和胆红素结合的比较。对于变体形式，未检测到[14C]棕榈酸、顺式-紫黄质酸或胆红素结合的差异。这些结果表明，与365位残基相邻的区域不太可能是这些配体中任何一种的主要结合位点的一部分。
