Mbelu Mamy, Kayembe Donatien, Mokassa Luc, Malemba Jean-Jacques
Service de Biologie Clinique, Cliniques Universitaires de Kinshasa, Kinshasa, République démocratique du Congo.
Service d´Orthopédie, Cliniques Universitaires de Kinshasa, Kinshasa, République démocratique du Congo.
Pan Afr Med J. 2020 Dec 4;37:314. doi: 10.11604/pamj.2020.37.314.25123. eCollection 2020.
the purpose of this study was to describe the profile of serum lipases in patients with bone fractures and to investigate the associated factors.
we conducted a cross-sectional study at the Kokolo Military General Hospital in Camp Kokolo (KMGHICK) from July to October 2013. All patients admitted with bone fractures who had agreed to take part in the study were included. The control group included voluntary blood donors. The parameters of interest were demographic characteristics, serum lipase, lipidogram, the site and the number of fractures.
eighty-three patients were included in the study, they were all male subjects. Mean age of patients was 35.8±12.8 years; 78.3% of fractures were due to gunshot-related trauma. Femur was the most common seat of fractures (30%), followed by forearm (20%) and ulna (15%). Mean serum lipase concentration was 43.6 ± 2.9 IU/L (normal value: ≤38IU/L) in patients with fractures compared with 30.3 ± 2.3 IU/L in the control group (p<0.0001).
a significantly higher rate of hyperlipasemia was found in patients with bone fractures compared with the control group. Hyperlipasemia was not associated with clinicobiological fatty embolism syndrome.
本研究旨在描述骨折患者血清脂肪酶的概况并调查相关因素。
2013年7月至10月，我们在科科洛营地的科科洛军事总医院（KMGHICK）进行了一项横断面研究。纳入所有同意参与研究的骨折入院患者。对照组包括自愿献血者。感兴趣的参数包括人口统计学特征、血清脂肪酶、血脂谱、骨折部位和骨折数量。
83名患者纳入研究，均为男性。患者平均年龄为35.8±12.8岁；78.3%的骨折由枪伤相关创伤所致。股骨是最常见的骨折部位（30%），其次是前臂（20%）和尺骨（15%）。骨折患者的平均血清脂肪酶浓度为43.6±2.9 IU/L（正常值：≤38IU/L），而对照组为30.3±2.3 IU/L（p<0.0001）。
与对照组相比，骨折患者中高脂血症发生率显著更高。高脂血症与临床生物学脂肪栓塞综合征无关。
