Ozkalayci Flora, Kocabas Umut, Altun Betul U, Pandi-Perumal Seithikurippu, Altun Armagan
Cardiology, Hisar Intercontinental Hospital, Istanbul, TUR.
Cardiology, Baskent University Izmir Hospital, Izmir, TUR.
Cureus. 2021 Jan 27;13(1):e12935. doi: 10.7759/cureus.12935.
Coronary artery disease (CAD) is one of the leading causes of morbidity and mortality worldwide. The coronary atherosclerotic process involves different pathological mechanisms; inflammation is one of the major triggers for the development of atherosclerotic plaque. Although several studies showed the favorable effects of melatonin on the cardiovascular system (CVS), melatonin seems not to take its rightful place in today's clinical practice. This review aims to point out the role of melatonin on cardiovascular disease (CVD) and its' risk factors. All data were obtained via PubMed, Wikipedia, and Google.
冠状动脉疾病（CAD）是全球发病和死亡的主要原因之一。冠状动脉粥样硬化过程涉及不同的病理机制；炎症是动脉粥样硬化斑块形成的主要触发因素之一。尽管多项研究表明褪黑素对心血管系统（CVS）有有益作用，但褪黑素在当今临床实践中似乎并未占据应有的地位。本综述旨在指出褪黑素在心血管疾病（CVD）及其危险因素中的作用。所有数据均通过PubMed、维基百科和谷歌获取。
