Landa Eric, Ganim Ismail, Vigandt Erika, Siraj Talhah, Zhu Ying
Internal Medicine, Unity Health, Searcy, USA.
Internal Medicine, Brooklyn Hospital, Brooklyn, USA.
Cureus. 2021 Jan 28;13(1):e12976. doi: 10.7759/cureus.12976.
There are 525 drugs that have been identified by the World Health Organization (WHO) as having the potential to cause pancreatitis. The most well-known drugs include mesalamine, azathioprine, and simvastatin, all of which have been well described in the literature. However, drug-induced pancreatitis only used to account for about 1%-2% of cases in the 1990s; this number has increased to up to 5% in some studies. By accounting for over 100,000 cases per year in the United States alone, it is important to be able to recognize these cases and act rapidly and appropriately to remove the offending agent. The vast majority of cases occur within six weeks of initiating or increasing the dosage of such medications. Here we present an interesting case of meloxicam-induced pancreatitis.
世界卫生组织(WHO)已确定有525种药物有可能导致胰腺炎。最知名的药物包括美沙拉嗪、硫唑嘌呤和辛伐他汀,所有这些药物在文献中都有详细描述。然而,药物性胰腺炎在20世纪90年代仅占病例的1%-2%;在一些研究中,这一数字已增至5%。仅在美国,每年就有超过10万例病例,因此能够识别这些病例并迅速采取适当行动去除致病药物非常重要。绝大多数病例发生在开始使用或增加此类药物剂量的六周内。在此,我们介绍一例有趣的美洛昔康诱发胰腺炎的病例。