慢性鼻窦炎术后清创术与非清创术的比较
Postoperative Debridement versus No Debridement in Chronic Rhinosinusitis.
作者信息
Rahavi-Ezabadi Sara, Amali Amin, Saedi Babak, Gilanifar Nafiseh, Mirashrafi Fatemeh
机构信息
Otorhinolaryngology Research Center, Department of Otorhinolaryngology Head and Neck Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Iran J Otorhinolaryngol. 2021 Jan;33(114):15-21. doi: 10.22038/ijorl.2020.43210.2417.
INTRODUCTION
This study aimed to assess the long-term effects of postoperative debridement on the 4 and 8 postoperative weeks versus no debridement in terms of subjective and objective outcomes.
MATERIALS AND METHODS
The statistical population of this study (n=80) consisted of 40 patients having chronic rhinosinusitis with nasal polyposis (CRSwNP) and 40 patients having chronic rhinosinusitis without nasal polyposis (CRSsNP). These samples were randomly divided into two groups of debridement and control.
RESULTS
According to the results, 8 weeks after endoscopic sinus surgery (ESS), the 22-item Sino-Nasal Outcome Test questionnaire score (P =0.03), Lund-Kennedy score (P<0.001), nasal blockage (P=0.02), and loss/decrease in sense of smell (P=0.02) in CRSwNP were significantly lower in the debridement group than in the control group. Moreover, 6 months after ESS, in both CRSwNP and CRSsNP, no significant difference was observed between the two groups considering the outcomes (P>0.05).
CONCLUSION
This study showed that debridement could lead to short-term improvements in CRSwNP patients; however, no long-term benefit was observed.
引言
本研究旨在评估术后清创与不清创相比，在术后4周和8周时对主观和客观结果的长期影响。
材料与方法
本研究的统计总体（n = 80）包括40例患有慢性鼻窦炎伴鼻息肉（CRSwNP）的患者和40例患有慢性鼻窦炎但无鼻息肉（CRSsNP）的患者。这些样本被随机分为清创组和对照组。
结果
根据结果，在鼻内镜鼻窦手术（ESS）8周后，CRSwNP患者中，清创组的22项鼻鼻窦结局测试问卷评分（P = 0.03）、Lund-Kennedy评分（P < 0.001）、鼻塞（P = 0.02）以及嗅觉丧失/减退（P = 0.02）均显著低于对照组。此外，在ESS术后6个月，考虑到各项结果，CRSwNP和CRSsNP两组之间均未观察到显著差异（P > 0.05）。
结论
本研究表明，清创可使CRSwNP患者获得短期改善；然而，未观察到长期益处。
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