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功能性内镜鼻窦手术后的鼻腔清创术:文献系统综述

Postoperative nasal debridement following functional endoscopic sinus surgery, a systematic review of the literature.

作者信息

Green R, Banigo A, Hathorn I

机构信息

Department of ENT, Lauriston Building, Edinburgh, UK.

出版信息

Clin Otolaryngol. 2015 Feb;40(1):2-8. doi: 10.1111/coa.12330.

Abstract

BACKGROUND

Chronic rhinosinusitis is a significant health problem, and the optimal postoperative treatment regime for patients post functional endoscopic sinus surgery has been a topic debated for years.

OBJECTIVE OF REVIEW

To systematically review and critically evaluate the evidence relating to postoperative debridement of the nasal cavity following functional endoscopic sinus surgery to guide best practice.

SEARCH STRATEGY

A search of the following databases was performed: Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effectiveness, and Cochrane Central Register of Control Trials. Ovid Medline, EMBASE, Pubmed. The following key words were used: Postoperative, functional endoscopic sinus surgery, sinus surgery, debridement, follow-up, from 1970 to 2013.

EVALUATION METHOD

Two independent reviewers assessed the relevant articles using the consort guidance on systematic reviews Moher et al. BMJ 2010; 340: c869.

RESULTS

The best evidence available was 1B, with six Randomsied control trial (RCTs) identified. Four studies compared debridement against no debridement, and two looked at the frequency of the debridement. Cumulatively, results for 337 patients were included. Visual analogue scores were used in all studies. None of the results at the long-term follow-up showed any difference in sino-nasal outcome test scores or objective endoscopic scores. Four of the six studies demonstrated some benefit in symptom scores but only one in the long term. Two papers demonstrated the debridement group suffered more pain in the postoperative period.

CONCLUSIONS

Currently, there is no clear evidence for frequent postoperative debridement. Further well-designed RCTs are required to establish clear benefit, optimal frequency, extent and timing of debridement.

摘要

背景

慢性鼻窦炎是一个严重的健康问题,功能性鼻内镜鼻窦手术后患者的最佳术后治疗方案多年来一直是一个备受争议的话题。

综述目的

系统回顾并严格评估与功能性鼻内镜鼻窦手术后鼻腔清创相关的证据,以指导最佳实践。

检索策略

对以下数据库进行了检索:Cochrane系统评价数据库、有效性评价文摘数据库和Cochrane对照试验中心注册库。Ovid Medline、EMBASE、Pubmed。使用了以下关键词:术后、功能性鼻内镜鼻窦手术、鼻窦手术、清创、随访,时间范围为1970年至2013年。

评估方法

两名独立的评审员根据系统评价的CONSORT指南(Moher等人,《英国医学杂志》2010年;340:c869)对相关文章进行评估。

结果

现有最佳证据为1B级,共识别出6项随机对照试验(RCT)。4项研究比较了清创与不清创的效果,2项研究观察了清创的频率。累计纳入337例患者的结果。所有研究均使用视觉模拟评分。长期随访结果显示,鼻窦结局测试评分或客观内镜评分均无差异。6项研究中的4项显示症状评分有一定益处,但长期来看只有1项如此。两篇论文表明清创组术后疼痛更严重。

结论

目前,尚无明确证据支持频繁进行术后清创。需要进一步设计良好的RCT来确定清创的明确益处、最佳频率、范围和时机。

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