Metz Christopher M, Standring Robert T, Babu Seilesh C, Keller Christian E
St John Providence Health System, Madison Heights, Michigan; St. John Providence Otolaryngology Division, Novi, MI.
St. John Providence Otolaryngology Division, Novi, MI; Ear Nose and Throat Consultants, Southfield MI.
Spartan Med Res J. 2019 Mar 4;3(3):7406. doi: 10.51894/001c.7406.
Inverted papilloma is a rare condition of the middle ear. In this paper, the authors present a case report of a patient at a Midwestern health system with inverted papilloma. To supplement the case report, a literature review was also performed to identify clinical trends predisposing such cases to recurrence, malignant transformation, and response to radiation. In addition, the authors also propose a surveillance algorithm derived from this case and previously published surveillance strategies.
The authors present a rare case of inverted papilloma of the middle ear. To the authors' knowledge, this is the youngest case presentation (mid-teenage years) of this condition to have been reported in the literature. The patient underwent surgical excision, had recurrence, and has been disease free since revision surgery.
Our literature review identified 25 cases previously published with ours being the 26th. An inadequate number of cases exist to abstract statically relevant clinical trends in presentation and tumor behavior. Additionally, no tumor characteristics have been identified that predispose tumors to future malignant transformation. No assessments can be made regarding the benefits of radiation therapy. Most cases to date have been surveyed with a combination of CT, MRI, and clinical follow-up.
Inverted papillomas of the middle ear space are rare. Although this case report adds to the literature, additional cases are needed to draw statistically relevant clinical characteristics and responses to medical and surgical therapy.
内翻性乳头状瘤是一种罕见的中耳疾病。在本文中,作者报告了一名中西部医疗系统中患有内翻性乳头状瘤的患者病例。为补充该病例报告,作者还进行了文献综述,以确定导致此类病例复发、恶变以及对放疗反应的临床趋势。此外,作者还根据该病例和先前发表的监测策略提出了一种监测算法。
作者报告了一例罕见的中耳内翻性乳头状瘤病例。据作者所知,这是文献报道中该疾病最年轻的病例(十几岁)。该患者接受了手术切除,出现了复发,自翻修手术后一直无病生存。
我们的文献综述发现之前已发表了25例病例,我们的病例是第26例。现有的病例数量不足以提取有关临床表现和肿瘤行为的具有统计学意义的临床趋势。此外,尚未发现有哪些肿瘤特征会使肿瘤易于发生未来的恶变。无法对放射治疗的益处进行评估。迄今为止,大多数病例采用CT、MRI和临床随访相结合的方式进行监测。
中耳内翻性乳头状瘤很罕见。尽管本病例报告丰富了文献内容,但仍需要更多病例来得出具有统计学意义的临床特征以及对药物和手术治疗的反应。