O'Neill Nicholas, Wisniewski Samuel J, Adams Michael, Peters James, Wagner Michael
McLaren Macomb Regional Medical Center.
Michigan State University College of Osteopathic Medicine.
Spartan Med Res J. 2019 Jul 1;4(1):8105. doi: 10.51894/001c.8105.
Recent advances in diagnostic imaging have made computed tomography (CT) a widely used test in trauma patients. Consequently, the collective radiation burdened sustained by this patient population has increased substantially. The purpose of this cadaveric study was to determine if a significantly lowered CT radiation dose protocol would provide adequate imaging studies for the surgeon, using the distal femur as a model.
Ten adult cadaveric knee specimens were used to create Orthopaedic Trauma Association (AO/OTA) 33-C3 distal femur fractures with associated coronal plane Hoffa fractures and varying intra-articular displacements. Using a single CT scanner, each cadaver was scanned at 5 separate protocols defined by sequentially lowered radiation doses, the highest of which was one-third the value of our institution's current protocol. These images were then evaluated by fellowship-trained orthopedic surgeons, an orthopedic trauma fellow, and residents. Observer reliability and confidence levels were calculated for measuring fracture displacement, assessing the quality of 3D reconstructions, and developing treatment plans.
Across all reviewers and specimens, there was an average difference of 0.66 millimeters (mm) between the measured fracture gap and true fracture gap. The highest intraclass correlation coefficient (ICC) calculated for the inter-rater reliability of gap measurements was 0.983 at 75 mAs (95% CI: 0.955-0.996), followed by 0.973 (95% CI: 0.930-0.993) and 0.958 (95% CI: 0.896-0.988) at 15 mAs and 60 mAs, respectively. All 3D reconstructions obtained at 75 mAs and 45 mAs values (N = 8) were of acceptable imaging quality to all reviewers, while only 3 of 4 3D reconstructions obtained at 15 mAs were considered acceptable. There was no difference in treatment plans across all reviewers, regardless of radiation dose.
In summary, our results indicate that CT scans of complex distal femur fractures at one-third the amount of radiation exposure may provide adequate imaging necessary to develop an appropriate treatment plan. At significantly lowered doses, the reviewers were able to accurately measure the amount of fracture displacement and identify the presence of each Hoffa fracture. Future studies are necessary to compare this protocol's diagnostic capacity and limitations in evaluating complex fractures with that of our institution's standard protocol in a clinical setting.
诊断成像技术的最新进展使计算机断层扫描(CT)成为创伤患者广泛使用的检查手段。因此,这一患者群体承受的累积辐射负担大幅增加。本尸体研究的目的是,以股骨远端为模型,确定大幅降低的CT辐射剂量方案是否能为外科医生提供足够的影像检查。
使用10个成年尸体膝关节标本制造出符合骨科创伤协会(AO/OTA)33-C3型的股骨远端骨折,并伴有冠状面Hoffa骨折及不同程度的关节内移位。使用一台CT扫描仪,按照依次降低的辐射剂量所定义的5种不同方案对每个尸体进行扫描,其中辐射剂量最高的方案是本机构当前方案剂量值的三分之一。然后,由接受过专科培训的骨科医生、一名骨科创伤专科住院医生和住院医师对这些图像进行评估。计算观察者在测量骨折移位、评估三维重建质量以及制定治疗方案方面的可靠性和信心水平。
在所有评估者和标本中测得的骨折间隙与实际骨折间隙之间的平均差值为0.66毫米(mm)。在75毫安秒(mAs)时,间隙测量的组内相关系数(ICC)计算得出的最高组间可靠性为0.983(95%置信区间:0.955 - 0.996),其次在15 mAs和60 mAs时分别为0.973(95%置信区间:0.930 - 0.993)和0.958(95%置信区间:0.896 - 0.988)。在75 mAs和45 mAs剂量值下获得的所有三维重建图像(N = 8)对所有评估者而言成像质量均可接受,而在15 mAs剂量值下获得的4幅三维重建图像中只有3幅被认为可接受。无论辐射剂量如何,所有评估者制定的治疗方案均无差异。
总之,我们的结果表明,以三分之一的辐射剂量对复杂的股骨远端骨折进行CT扫描,可能会提供制定合适治疗方案所需的足够影像。在大幅降低剂量的情况下,评估者能够准确测量骨折移位量并识别每例Hoffa骨折的存在。未来有必要开展研究,在临床环境中将此方案与本机构标准方案在评估复杂骨折方面的诊断能力和局限性进行比较。