From the Duke Clinical Research Institute and Department of Radiology, Duke University School of Medicine, PO Box 17969, 2400 Pratt St, Durham, NC 27715.
Radiology. 2014 Nov;273(2 Suppl):S45-74. doi: 10.1148/radiol.14141356.
Computed tomography (CT) has had a profound effect on the practice of medicine. Both the spectrum of clinical applications and the role that CT has played in enhancing the depth of our understanding of disease have been profound. Although almost 90 000 articles on CT have been published in peer-reviewed journals over the past 40 years, fewer than 5% of these have been published in Radiology. Nevertheless, these almost 4000 articles have provided a basis for many important medical advances. By enabling a deepened understanding of anatomy, physiology, and pathology, CT has facilitated key advances in the detection and management of disease. This article celebrates this breadth of scientific discovery and development by examining the impact that CT has had on the diagnosis, characterization, and management of a sampling of major health challenges, including stroke, vascular diseases, cancer, trauma, acute abdominal pain, and diffuse lung diseases, as related to key technical advances in CT and manifested in Radiology.
计算机断层扫描（CT）对医学实践产生了深远的影响。CT 的临床应用范围和在加深我们对疾病认识方面所起的作用都非常深刻。尽管在过去的 40 年里，在同行评议的期刊上发表了近 90000 篇关于 CT 的文章，但其中只有不到 5%发表在放射学领域。然而，这近 4000 篇文章为许多重要的医学进展提供了基础。通过加深对解剖、生理和病理的理解，CT 促进了疾病检测和管理方面的重大进展。本文通过检查 CT 在诊断、特征描述和处理一系列主要健康挑战方面的影响，包括中风、血管疾病、癌症、创伤、急性腹痛和弥漫性肺部疾病，来庆祝这一广泛的科学发现和发展，这些挑战与 CT 的关键技术进步有关，并在放射学中得到体现。
