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软骨下成形术治疗与骨髓损伤相关的膝关节疼痛的疗效

The Efficacy of Subchondroplasty for the Treatment of Knee Pain Associated with Bone Marrow Lesions.

作者信息

Krebs Nathan M, Kehoe James L, Van Wagner Michael J, Rios-Bedoya Carlos

机构信息

Mercy Health.

McLaren Macomb Medical Center.

出版信息

Spartan Med Res J. 2020 Jan 30;4(2):11767. doi: 10.51894/001c.11767.

Abstract

CONTEXT

Symptomatic bone marrow lesions on MRI in patients with knee osteoarthritis are strongly associated with progressive deterioration of the joint and an increased risk of progression requiring joint replacement surgery. This study evaluates the efficacy of knee arthroscopy with adjunctive subchondroplasty (i.e. cartilage stabilization) to improve self-rated visual analog scale (VAS) pain scores, rate of conversion to arthroplasty, and patient satisfaction levels.

METHODS

A retrospective chart review and phone survey was performed on 12 patients who had undergone knee arthroscopy with adjunctive subchondroplasty for knee pain associated with chronic subchondral bone marrow lesions on MRI. Follow-up for the 12 patients was 36 months on average (range of 12 to 51 months), self-reported paired preoperative and postoperative VAS scores were analyzed in addition to rate of conversion to arthroplasty and patient satisfaction.

RESULTS

The results demonstrated statistically significant reductions in mean preoperative VAS scores versus six-week postoperative VAS scores from 7.58 to 1.83 (p < 0.001) in addition to significant reductions in mean preoperative VAS scores to final postoperative VAS scores from 7.58 to 1.60 (p < 0.001). There was no statistically significant association (p > 0.05) with patients' demographic and clinical data (e.g., age, height, weight, BMI, length of symptoms) and rate of revision to total arthroplasty after receiving the arthroscopic subchondroplasty procedure. Out of the 12 patients, two (16.7%) patients went on to conversion to total knee arthroplasty.

CONCLUSIONS

In this series, knee arthroscopy with adjunctive subchondroplasty for the treatment of osteoarthritis with symptomatic bone marrow lesions was associated with clinically significant improvements in VAS pain scores. Furthermore, patients who underwent subchondroplasty had a low rate (16.7%) of conversion to total knee arthroplasty at 36-month follow-up.

摘要

背景

膝关节骨关节炎患者磁共振成像(MRI)上有症状的骨髓病变与关节的渐进性恶化以及需要进行关节置换手术的进展风险增加密切相关。本研究评估膝关节镜检查联合软骨下成形术(即软骨稳定术)改善自我评定的视觉模拟量表(VAS)疼痛评分、转换为关节置换术的比率以及患者满意度的疗效。

方法

对12例因MRI显示慢性软骨下骨髓病变而接受膝关节镜检查联合软骨下成形术治疗膝关节疼痛的患者进行回顾性病历审查和电话调查。12例患者的平均随访时间为36个月(范围为12至51个月),分析了术前和术后自我报告的配对VAS评分,以及转换为关节置换术的比率和患者满意度。

结果

结果显示,术前平均VAS评分与术后六周VAS评分相比有统计学意义的降低,从7.58降至1.83(p < 0.001),术前平均VAS评分与术后最终VAS评分相比也有显著降低,从7.58降至1.60(p < 0.001)。接受关节镜下软骨下成形术后,患者的人口统计学和临床数据(如年龄、身高、体重、BMI、症状持续时间)与全关节置换术翻修率之间无统计学意义的关联(p > 0.05)。12例患者中,有2例(16.7%)患者最终转换为全膝关节置换术。

结论

在本系列研究中,膝关节镜检查联合软骨下成形术治疗有症状骨髓病变的骨关节炎与VAS疼痛评分的临床显著改善相关。此外,在36个月的随访中,接受软骨下成形术的患者转换为全膝关节置换术的比率较低(16.7%)。

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