Nishiura M, Izumi S, Mori T, Takeo K, Nonaka T
Int J Lepr Other Mycobact Dis. 1977 Jul-Sep;45(3):248-54.
Morphologic features of the electron transparent zone (ETZ) material around human and murine leprosy bacilli were examined by a freeze-etching technic. The ETZ around human leprosy bacilli is composed of spherical droplets of hydrophobic material. These are always liquid at body temperature and they never show crystalline lamellar structure even at the temperature of liquid nitrogen. The ETZ around murine leprosy bacilli is composed of ribbon-like or membranous crystalline structures. This material is solid and crystalline at the body temperature of mice, and this solid material is the chief cause of the random arrangement of murine leprosy bacilli inside the cytoplasm of murine lepra cells. This crystalline structure has also been observed around murine leprosy bacilli grown on cell-free culture media.
采用冷冻蚀刻技术研究了人和鼠麻风杆菌周围电子透明区（ETZ）物质的形态特征。人麻风杆菌周围的ETZ由疏水性物质的球形液滴组成。这些液滴在体温下始终呈液态，即使在液氮温度下也从未显示出晶体层状结构。鼠麻风杆菌周围的ETZ由带状或膜状晶体结构组成。这种物质在小鼠体温下是固态且呈晶体状，这种固态物质是鼠麻风杆菌在鼠麻风细胞胞质内随机排列的主要原因。在无细胞培养基上生长的鼠麻风杆菌周围也观察到了这种晶体结构。
