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可见光驱动且自供氢的纳米纤维实现快速部署的抗菌生物防护。

Visible-Light-Driven and Self-Hydrogen-Donated Nanofibers Enable Rapid-Deployable Antimicrobial Bioprotection.

机构信息

State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Textiles, Donghua University, Shanghai, 201620, China.

College of Materials Science and Engineering, Donghua University, Shanghai, 201620, China.

出版信息

Small. 2021 Mar;17(12):e2100139. doi: 10.1002/smll.202100139. Epub 2021 Mar 3.

DOI:10.1002/smll.202100139
PMID:33656273
Abstract

The novel coronavirus SARS-CoV-2 has prompted a worldwide pandemic and poses a great threat to public safety and global economies. Most present personal protective equipment (PPE) used to intercept pathogenic microorganisms is deficient in biocidal properties. Herein, we present green nanofibers with effective antibacterial and antiviral activities that can provide sustainable bioprotection by continuously producing reactive oxygen species (ROS). The superiority of the design is that the nanofibers can absorb and store visible light energy and maintain the activity under light or dark environment. Moreover, the nanofibers can uninterruptedly release ROS in the absence of an external hydrogen donor, acting as a biocide under all weather conditions. A facile spraying method is proposed to rapidly deploy the functional nanofibers to existing PPE, such as protective suits and masks. The modified PPE exhibit stable ROS production, excellent capacity for storing activity potential, long-term durability, and high bactericidal (>99.9%) and viricidal (>99.999%) efficacies.

摘要

新型冠状病毒 SARS-CoV-2 引发了全球性大流行,对公众安全和全球经济构成了巨大威胁。目前大多数用于拦截致病微生物的个人防护设备(PPE)在杀菌性能方面存在不足。在此,我们提出了具有有效抗菌和抗病毒活性的绿色纳米纤维,通过持续产生活性氧(ROS)来提供可持续的生物保护。该设计的优势在于纳米纤维可以吸收和储存可见光能量,并在光照或黑暗环境下保持活性。此外,纳米纤维在没有外部氢供体的情况下可以不间断地释放 ROS,在任何天气条件下都能充当杀菌剂。我们提出了一种简便的喷涂方法,可快速将功能性纳米纤维部署到现有的 PPE 上,如防护服和口罩。经过改性的 PPE 表现出稳定的 ROS 产生、出色的储存活性能力、长期耐用性以及高效的杀菌(>99.9%)和杀病毒(>99.999%)功效。

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