Department of Cardiovascular and Thoracic Surgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Braz J Cardiovasc Surg. 2022 May 2;37(2):185-193. doi: 10.21470/1678-9741-2020-0147.
Type A acute aortic dissection (AAD) remains a challenging cardiac emergency despite the availability of various management strategies. This study compared the outcomes of supracoronary ascending aortic replacement (SCAAR) with aortic valve (AV) resuspension with those of modified Bentall's operation for type A AAD and the progression of aortic regurgitation (AR), long-term dilatation of aortic root and proximal arch, and long-term mortality in SCAAR patients.
Sixty patients underwent surgery for type A AAD (January 2005 to December 2015). Forty-three patients underwent SCAAR with AV resuspension and 17 underwent modified Bentall's operation. All patients were followed up.
Upon follow-up of SCAAR patients (n=40), there was significant reduction in aortic root size (preoperative 39.3 mm [9.4] vs. postoperative 33.1 mm [9.1]; P<0.001). Three of these patients worsened to severe AR while others had similar or lesser degree of AR. On comparison between preoperative and postoperative dimensions of all patients (n=53), there was no significant difference in distal ascending aorta size (35.7 mm [8.1] vs. 34.4 mm [8.9]; P=0.52). However, an increase in descending thoracic aorta size (28.8 mm [7.8] vs. 33.7 mm [9.9]; P<0.001) was observed. In-hospital and late mortalities for SCAAR vs. modified Bentall's procedure were 11.7% (seven patients) (7% [3] vs. 23.5% [4]) and 28% (15 patients) (15% [6] vs. 69% [9]), respectively.
SCAAR with AV resuspension is a safe surgical option for type A AAD. Preservation of AV is associated with better long-term outcomes and reduced mortality. Modified Bentall's operation may be associated with long-term mortality.
尽管有多种管理策略可供选择,但 A 型急性主动脉夹层(AAD)仍然是一种具有挑战性的心脏急症。本研究比较了升主动脉弓置换术(SCAAR)联合主动脉瓣(AV)悬吊术与改良 Bentall 手术治疗 A 型 AAD 的疗效,以及 SCAAR 患者主动脉瓣反流(AR)的进展、主动脉根部和近端弓的长期扩张以及长期死亡率。
2005 年 1 月至 2015 年 12 月,60 例 A 型 AAD 患者接受手术治疗。43 例患者接受 SCAAR 联合 AV 悬吊术,17 例患者接受改良 Bentall 手术。所有患者均接受随访。
SCAAR 患者(n=40)随访时主动脉根部大小明显缩小(术前 39.3mm[9.4] vs. 术后 33.1mm[9.1];P<0.001)。其中 3 例患者 AR 加重至重度,其他患者 AR 程度相似或较轻。比较所有患者(n=53)术前和术后的主动脉升段尺寸,远端升主动脉尺寸无显著差异(35.7mm[8.1] vs. 34.4mm[8.9];P=0.52)。然而,降主动脉尺寸增大(28.8mm[7.8] vs. 33.7mm[9.9];P<0.001)。SCAAR 与改良 Bentall 手术的院内和晚期死亡率分别为 11.7%(7 例)(7%[3] vs. 23.5%[4])和 28%(15 例)(15%[6] vs. 69%[9])。
SCAAR 联合 AV 悬吊术治疗 A 型 AAD 是一种安全的手术选择。保留 AV 与更好的长期预后和降低死亡率相关。改良 Bentall 手术可能与长期死亡率相关。