Genomic Laboratory (GLAB), Umraniye Teaching and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Cerrahpasa Faculty of Medicine, Department of Nephrology, Istanbul University-Cerrahpasa, Istanbul, Turkey.
PLoS One. 2021 Mar 3;16(3):e0247865. doi: 10.1371/journal.pone.0247865. eCollection 2021.
COVID-19 is a global threat with an increasing number of infections. Research on IgG seroprevalence among health care workers (HCWs) is needed to re-evaluate health policies. This study was performed in three pandemic hospitals in Istanbul and Kocaeli. Different clusters of HCWs were screened for SARS-CoV-2 infection. Seropositivity rate among participants was evaluated by chemiluminescent microparticle immunoassay. We recruited 813 non-infected and 119 PCR-confirmed infected HCWs. Of the previously undiagnosed HCWs, 22 (2.7%) were seropositive. Seropositivity rates were highest for cleaning staff (6%), physicians (4%), nurses (2.2%) and radiology technicians (1%). Non-pandemic clinic (6.4%) and ICU (4.3%) had the highest prevalence. HCWs in "high risk" group had similar seropositivity rate with "no risk" group (2.9 vs 3.5 p = 0.7). These findings might lead to the re-evaluation of infection control and transmission dynamics in hospitals.
新型冠状病毒肺炎是一种具有日益增多感染病例的全球威胁。需要对卫生保健工作者（HCWs）的 IgG 血清流行率进行研究，以重新评估卫生政策。本研究在伊斯坦布尔和科贾埃利的三家大流行医院进行。对 SARS-CoV-2 感染的 HCWs 不同群体进行了筛查。通过化学发光微粒子免疫分析评估参与者的血清阳性率。我们招募了 813 名未感染和 119 名 PCR 确诊感染的 HCWs。在先前未诊断的 HCWs 中，有 22 名（2.7%）呈血清阳性。清洁人员（6%）、医生（4%）、护士（2.2%）和放射科技术人员（1%）的血清阳性率最高。非大流行科室（6.4%）和 ICU（4.3%）的患病率最高。“高危”组和“无风险”组的血清阳性率相似（2.9%比 3.5%，p=0.7）。这些发现可能导致重新评估医院的感染控制和传播动态。
