土耳其三家大流行医院医护人员中 2019 年冠状病毒病（COVID-19）血清流行率。
Seroprevalence of coronavirus disease 2019 (COVID-19) among health care workers from three pandemic hospitals of Turkey.
机构信息
Genomic Laboratory (GLAB), Umraniye Teaching and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Cerrahpasa Faculty of Medicine, Department of Nephrology, Istanbul University-Cerrahpasa, Istanbul, Turkey.
出版信息
PLoS One. 2021 Mar 3;16(3):e0247865. doi: 10.1371/journal.pone.0247865. eCollection 2021.
COVID-19 is a global threat with an increasing number of infections. Research on IgG seroprevalence among health care workers (HCWs) is needed to re-evaluate health policies. This study was performed in three pandemic hospitals in Istanbul and Kocaeli. Different clusters of HCWs were screened for SARS-CoV-2 infection. Seropositivity rate among participants was evaluated by chemiluminescent microparticle immunoassay. We recruited 813 non-infected and 119 PCR-confirmed infected HCWs. Of the previously undiagnosed HCWs, 22 (2.7%) were seropositive. Seropositivity rates were highest for cleaning staff (6%), physicians (4%), nurses (2.2%) and radiology technicians (1%). Non-pandemic clinic (6.4%) and ICU (4.3%) had the highest prevalence. HCWs in "high risk" group had similar seropositivity rate with "no risk" group (2.9 vs 3.5 p = 0.7). These findings might lead to the re-evaluation of infection control and transmission dynamics in hospitals.
新型冠状病毒肺炎是一种具有日益增多感染病例的全球威胁。需要对卫生保健工作者（HCWs）的 IgG 血清流行率进行研究，以重新评估卫生政策。本研究在伊斯坦布尔和科贾埃利的三家大流行医院进行。对 SARS-CoV-2 感染的 HCWs 不同群体进行了筛查。通过化学发光微粒子免疫分析评估参与者的血清阳性率。我们招募了 813 名未感染和 119 名 PCR 确诊感染的 HCWs。在先前未诊断的 HCWs 中，有 22 名（2.7%）呈血清阳性。清洁人员（6%）、医生（4%）、护士（2.2%）和放射科技术人员（1%）的血清阳性率最高。非大流行科室（6.4%）和 ICU（4.3%）的患病率最高。“高危”组和“无风险”组的血清阳性率相似（2.9%比 3.5%，p=0.7）。这些发现可能导致重新评估医院的感染控制和传播动态。
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