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中国 115 例新型冠状病毒肺炎(COVID-19)恢复期患者肺部 CT 病变与支气管扩张症的临床研究。

Clinical study of pulmonary CT lesions and associated bronchiectasis in 115 convalescent patients with novel coronavirus pneumonia (COVID-19) in China.

机构信息

Department of Stomatology, Wuhan No. 1 Hospital (Wuhan Hospital of Traditional Chinese & Western Medicine), Wuhan City, Hubei Province 430022, China.

Department of Cardiovascular Medicine, Wuhan No. 1 Hospital (Wuhan Hospital of Traditional Chinese & Western Medicine), Wuhan City, Hubei Province 430022, China.

出版信息

Can J Physiol Pharmacol. 2021 Mar;99(3):328-331. doi: 10.1139/cjpp-2020-0522. Epub 2021 Mar 3.

DOI:10.1139/cjpp-2020-0522
PMID:33657328
Abstract

A total of 115 convalescent inpatients with COVID-19 were enrolled. According to the results of scans of lung lesions via computed tomography (CT), the patients were divided into mild, moderate, and severe groups. The clinical data of the patients were collected, including age, gender, finger pulse oxygen pressure, ventricular rate, body temperature, etc. The correlation between the clinical indicators and the lesions of high-resolution CT (HRCT) and bronchiectasis was analyzed. Among the 115 patients, 82 had no bronchiectasis and 33 had bronchiectasis. The bronchodilation-prone layers mainly included the left and right lower lobe of the lung. The probability of branching in the inflamed area was greater than that in the noninflamed area in patients with COVID-19. There were significant differences in gender, CT lesion range, and number of incidents of bronchiectasis between noninflamed and inflamed areas ( < 0.05). Moreover, there were significant differences in age, total proportion of CT lesions, volume of CT lesions, and total number of patients with bronchiectasis among the three groups ( < 0.05). CT lesion range was positively correlated with the total number of patients with bronchiectasis and patient age (respectively, = 0.186, < 0.05; = 0.029, < 0.05). The lesion range in HRCT images of lungs in patients with COVID-19 is correlated with bronchodilation. The larger the lesion, the higher the probability of bronchiectasis and the more incidents of bronchiectasis.

摘要

共纳入 115 例 COVID-19 恢复期住院患者。根据肺部病变 CT 扫描结果,将患者分为轻症、中度和重症组。收集患者的临床资料,包括年龄、性别、指脉氧饱和度、心室率、体温等。分析临床指标与高分辨率 CT(HRCT)和支气管扩张病变的相关性。115 例患者中,82 例无支气管扩张,33 例有支气管扩张。支气管扩张易患层主要为左右肺下叶。COVID-19 患者病变区分支的概率大于非病变区。非病变区和病变区在性别、CT 病变范围、支气管扩张发生率等方面存在显著差异(<0.05)。此外,三组之间在年龄、CT 病变总比例、CT 病变体积和支气管扩张患者总数等方面存在显著差异(<0.05)。CT 病变范围与支气管扩张患者总数和患者年龄呈正相关(分别=0.186,<0.05;=0.029,<0.05)。COVID-19 患者肺部 HRCT 图像的病变范围与支气管扩张有关。病变范围越大,支气管扩张的概率越高,支气管扩张的发生率越高。

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