Multidisciplinary Sleep Unit, Respiratory Department, Sant Joan University Hospital, Sant Joan d'Alacant, Alicante, Spain.
Respiratory Department, Salamanca University Hospital, Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
Arch Bronconeumol. 2022 Apr;58 Suppl 1:39-50. doi: 10.1016/j.arbres.2022.03.011. Epub 2022 Apr 15.
On March 11, 2020, the World Health Organization declared Coronavirus Disease 2019 (COVID-19) a pandemic. Till now, it affected 452.4 million (Spain, 11.18 million) persons all over the world with a total of 6.04 million of deaths (Spain, 100,992). It is observed that 75% of hospitalized COVID-19 patients have at least one COVID-19 associated comorbidity. It was shown that people with underlying chronic illnesses are more likely to get it and grow seriously ill. Individuals with COVID-19 who have a past medical history of cardiovascular disorder, cancer, obesity, chronic lung disease, diabetes, or neurological disease had the worst prognosis and are more likely to develop acute respiratory distress syndrome or pneumonia. COVID-19 can affect the respiratory system in a variety of ways and across a spectrum of levels of disease severity, depending on a person's immune system, age and comorbidities. Symptoms can range from mild, such as cough, shortness of breath and fever, to critical disease, including respiratory failure, shock and multi-organ system failure. So, COVID-19 infection can cause overall worsening of these previous respiratory diseases, such as asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease, etc. This review aims to provide information on the impact of the COVID-19 disease on pre-existing lung comorbidities.
2020 年 3 月 11 日,世界卫生组织宣布 2019 年冠状病毒病(COVID-19)为大流行。迄今为止,它已影响全球 4.524 亿人(西班牙 1118 万人),总共有 604 万人死亡(西班牙 100992 人)。据观察,75%的住院 COVID-19 患者至少有一种 COVID-19 相关合并症。研究表明,患有潜在慢性疾病的人更容易感染 COVID-19 并病情加重。患有 COVID-19 的人如果有心血管疾病、癌症、肥胖、慢性肺病、糖尿病或神经系统疾病的既往病史,预后最差,更容易发展为急性呼吸窘迫综合征或肺炎。COVID-19 可以通过多种方式影响呼吸系统,并在疾病严重程度的各个范围内,这取决于一个人的免疫系统、年龄和合并症。症状从轻微的咳嗽、呼吸急促和发热到严重疾病,包括呼吸衰竭、休克和多器官系统衰竭。因此,COVID-19 感染可能会导致这些先前的呼吸系统疾病(如哮喘、慢性阻塞性肺疾病(COPD)、间质性肺病等)的整体恶化。本综述旨在提供关于 COVID-19 疾病对现有肺部合并症影响的信息。