National Centre of Healthcare Research & Pharmacoepidemiology.
Department of Statistics and Quantitative Methods, Unit of Biostatistics, Epidemiology and Public Health, University of Milano-Bicocca, Milan.
J Hypertens. 2021 May 1;39(5):856-860. doi: 10.1097/HJH.0000000000002833.
Several online sources provide up-to-date open-access data on numbers, rates and proportions of COVID-19 deaths. Our article aims of comparing and interpreting between-country trends of mortality rate, case-fatality and all-cause excess mortality.
We used data from open databases (Our World in Data mostly) for comparing mortality of eleven western countries (Austria, Belgium, Canada, France, Germany, Italy, Netherlands, Spain, Sweden, UK, USA). Between-country trends in mortality rate and case-fatality (both including deaths for COVID-19 as numerator and therefore labelled as COVID-19 mortality metrics) and all-cause excess mortality (i.e. observed deaths during the epidemic compared with those expected based on mortality in the same periods of previous years) were compared.
Although Belgium ranks first in mortality from COVID-19 (possibly due to the broadest criterion for attributing a death to COVID-19), it does not rank first for all-cause excess mortality. Conversely, compared with Belgium, the UK, Italy and Spain have reported lower COVID-19 mortality (possibly due to the narrower definitions for a COVID-19 death) but higher all-cause excess mortality. Germany and Austria are the unique countries for which COVID-19 mortality, case-fatality and all-cause excess mortality consistently exhibited the lowest rates.
Between-country heterogeneity of COVID-19 mortality metrics could be largely explained by differences of criteria for attributing a death to COVID-19; in age/comorbidity structures; in policies for identifying asymptomatic people affected from SARS-CoV-2 infection. All-cause excess mortality is recommended as a more reliable metric for comparing countries.
有几个在线资源提供了最新的 COVID-19 死亡人数、比率和比例的开放获取数据。我们的文章旨在比较和解释各国死亡率、病死率和全因超额死亡率的趋势。
我们使用了开放数据库(主要是 Our World in Data)的数据,比较了 11 个西方国家(奥地利、比利时、加拿大、法国、德国、意大利、荷兰、西班牙、瑞典、英国和美国)的死亡率。比较了死亡率和病死率(均包括 COVID-19 作为分子的死亡人数,因此标记为 COVID-19 死亡率指标)以及全因超额死亡率(即疫情期间观察到的死亡人数与前几年同期预期的死亡人数相比)的国家间趋势。
尽管比利时的 COVID-19 死亡率排名第一(可能是由于 COVID-19 死亡归因的标准最广泛),但它并不是全因超额死亡率排名第一的国家。相反,与比利时相比,英国、意大利和西班牙报告的 COVID-19 死亡率较低(可能是由于 COVID-19 死亡的定义较窄),但全因超额死亡率较高。德国和奥地利是 COVID-19 死亡率、病死率和全因超额死亡率一直较低的独特国家。
COVID-19 死亡率指标的国家间异质性可以很大程度上解释为归因于 COVID-19 的死亡标准的差异;在年龄/合并症结构;在识别受 SARS-CoV-2 感染影响的无症状人群的政策方面。全因超额死亡率被推荐作为比较国家的更可靠指标。