症状性外周动脉疾病患者的基因表达特征。
Gene Expression Signature in Patients With Symptomatic Peripheral Artery Disease.
机构信息
Division of Cardiology and the Center for the Prevention of Cardiovascular Disease (J.D.N., J.S.H., J.S.B.).
Division of Translational Medicine (M.G.C., K.V.R.), New York University School of Medicine, NY.
出版信息
Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1521-1533. doi: 10.1161/ATVBAHA.120.315857. Epub 2021 Mar 4.
Abstract
[Figure: see text].
摘要
[图：见正文]。
相似文献
1
Gene Expression Signature in Patients With Symptomatic Peripheral Artery Disease.症状性外周动脉疾病患者的基因表达特征。
Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1521-1533. doi: 10.1161/ATVBAHA.120.315857. Epub 2021 Mar 4.
2
Identification of Transcriptomic Differences between Lower Extremities Arterial Disease, Abdominal Aortic Aneurysm and Chronic Venous Disease in Peripheral Blood Mononuclear Cells Specimens.在外周血单核细胞标本中识别下肢动脉疾病、腹主动脉瘤和慢性静脉疾病之间的转录组差异。
Int J Mol Sci. 2021 Mar 21;22(6):3200. doi: 10.3390/ijms22063200.
3
Genetics of peripheral artery disease.外周动脉疾病的遗传学
Circulation. 2012 Jun 26;125(25):3220-8. doi: 10.1161/CIRCULATIONAHA.111.033878.
4
MicroRNA‑93 regulates angiogenesis in peripheral arterial disease by targeting CDKN1A.MicroRNA-93 通过靶向 CDKN1A 调节外周动脉疾病中的血管生成。
Mol Med Rep. 2019 Jun;19(6):5195-5202. doi: 10.3892/mmr.2019.10196. Epub 2019 Apr 25.
5
miR-548j-5p regulates angiogenesis in peripheral artery disease.miR-548j-5p 调控外周动脉疾病中的血管生成。
Sci Rep. 2022 Jan 17;12(1):838. doi: 10.1038/s41598-022-04770-6.
6
Acute and chronic effects of exercise on mRNA expression in the skeletal muscle of two mouse models of peripheral artery disease.运动对两种外周动脉疾病小鼠模型骨骼肌中mRNA表达的急性和慢性影响。
PLoS One. 2017 Aug 3;12(8):e0182456. doi: 10.1371/journal.pone.0182456. eCollection 2017.
7
Repetitive remote occlusion (RRO) stimulates eNOS-dependent blood flow and collateral expansion in hindlimb ischemia.重复远程闭塞（RRO）可刺激后肢缺血模型中内皮型一氧化氮合酶（eNOS）依赖性血流和侧支扩张。
Free Radic Biol Med. 2018 Dec;129:520-531. doi: 10.1016/j.freeradbiomed.2018.10.399. Epub 2018 Oct 15.
8
Identification and functional analysis of microRNAs in rats following focal cerebral ischemia injury.局灶性脑缺血损伤后大鼠 microRNAs 的鉴定和功能分析。
Mol Med Rep. 2019 May;19(5):4175-4184. doi: 10.3892/mmr.2019.10073. Epub 2019 Mar 21.
9
Skeletal muscle expression of adipose-specific phospholipase in peripheral artery disease.外周动脉疾病中脂肪特异性磷酸酶在骨骼肌中的表达。
Vasc Med. 2020 Oct;25(5):401-410. doi: 10.1177/1358863X20947467. Epub 2020 Aug 27.
10
[Advances in research on the genetics of peripheral arterial disease].[外周动脉疾病遗传学研究进展]
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2015 Dec;32(6):890-3. doi: 10.3760/cma.j.issn.1003-9406.2015.06.030.
引用本文的文献
1
Coronary Artery Disease and Atherosclerosis in Other Vascular Districts: Epidemiology, Risk Factors and Atherosclerotic Plaque Features.冠状动脉疾病与其他血管区域的动脉粥样硬化：流行病学、危险因素及动脉粥样硬化斑块特征
Life (Basel). 2025 Aug 3;15(8):1226. doi: 10.3390/life15081226.
2
miRNA-6236 Regulation of Postischemic Skeletal Muscle Angiogenesis.微小RNA-6236对缺血后骨骼肌血管生成的调控
J Am Heart Assoc. 2024 Dec 3;13(23):e035923. doi: 10.1161/JAHA.124.035923. Epub 2024 Nov 27.
3
A Platelet Reactivity ExpreSsion Score derived from patients with peripheral artery disease predicts cardiovascular risk.外周动脉疾病患者的血小板反应性表达评分可预测心血管风险。
Nat Commun. 2024 Aug 20;15(1):6902. doi: 10.1038/s41467-024-50994-7.
4
Paired Transcriptomic Analyses of Atheromatous and Control Vessels Reveal Novel Autophagy and Immunoregulatory Genes in Peripheral Artery Disease.动脉粥样硬化和对照血管的配对转录组分析揭示了外周动脉疾病中新型自噬和免疫调节基因。
Cells. 2024 Jul 28;13(15):1269. doi: 10.3390/cells13151269.
5
Single-Nuclei RNA-Sequencing of the Gastrocnemius Muscle in Peripheral Artery Disease.腓肠肌的单核 RNA 测序在周围动脉疾病中的应用。
Circ Res. 2023 Oct 27;133(10):791-809. doi: 10.1161/CIRCRESAHA.123.323161. Epub 2023 Oct 12.
6
Unveiling the Genetic Footprint: Exploring Somatic Mutations in Peripheral Arterial Disease Progression.揭示基因印记：探索外周动脉疾病进展中的体细胞突变
Biomedicines. 2023 Aug 17;11(8):2288. doi: 10.3390/biomedicines11082288.
7
Multiomics Analyses of Peripheral Artery Disease Muscle Biopsies.外周动脉疾病肌肉活检的多组学分析
Circ Res. 2023 May 26;132(11):1444-1446. doi: 10.1161/CIRCRESAHA.123.322913. Epub 2023 May 25.
8
Transcriptomic and Proteomic of Gastrocnemius Muscle in Peripheral Artery Disease.腓肠肌在周围动脉疾病中的转录组学和蛋白质组学研究。
Circ Res. 2023 May 26;132(11):1428-1443. doi: 10.1161/CIRCRESAHA.122.322325. Epub 2023 May 8.
9
An inflammatory transcriptomic signature in psoriasis associates with future cardiovascular events.银屑病中的炎症转录组特征与未来心血管事件相关。
J Eur Acad Dermatol Venereol. 2023 Jul;37(7):1361-1365. doi: 10.1111/jdv.19049. Epub 2023 Mar 22.
10
Integrating Mechanisms in Thrombotic Peripheral Arterial Disease.血栓性外周动脉疾病的整合机制
Pharmaceuticals (Basel). 2022 Nov 18;15(11):1428. doi: 10.3390/ph15111428.
本文引用的文献
1
Diabetes mellitus and outcomes of lower extremity revascularization for peripheral artery disease.糖尿病与下肢动脉病变血运重建治疗结局的关系。
Eur Heart J Qual Care Clin Outcomes. 2022 May 5;8(3):298-306. doi: 10.1093/ehjqcco/qcaa095.
2
Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor).丝氨酸磷酸化的前蛋白转化酶枯草溶菌素 9（Proprotein Convertase Subtilisin-Kexin 9）通过 Fam20C（家族与序列相似性 20，成员 C）激酶增强其降解 LDLR（低密度脂蛋白受体）的能力。
Arterioscler Thromb Vasc Biol. 2019 Oct;39(10):1996-2013. doi: 10.1161/ATVBAHA.119.313247. Epub 2019 Sep 5.
3
Genome-wide association study of peripheral artery disease in the Million Veteran Program.在百万退伍军人计划中进行的外周动脉疾病全基因组关联研究。
Nat Med. 2019 Aug;25(8):1274-1279. doi: 10.1038/s41591-019-0492-5. Epub 2019 Jul 8.
4
MicroRNA-615-5p Regulates Angiogenesis and Tissue Repair by Targeting AKT/eNOS (Protein Kinase B/Endothelial Nitric Oxide Synthase) Signaling in Endothelial Cells.MicroRNA-615-5p 通过靶向内皮细胞中的 AKT/eNOS（蛋白激酶 B/内皮型一氧化氮合酶）信号通路调节血管生成和组织修复。
Arterioscler Thromb Vasc Biol. 2019 Jul;39(7):1458-1474. doi: 10.1161/ATVBAHA.119.312726. Epub 2019 May 16.
5
Atheroprotective Flow Upregulates ITPR3 (Inositol 1,4,5-Trisphosphate Receptor 3) in Vascular Endothelium via KLF4 (Krüppel-Like Factor 4)-Mediated Histone Modifications.抗动脉粥样硬化血流通过 KLF4（Krüppel 样因子 4）介导的组蛋白修饰作用在上皮细胞中上调 ITPR3（三磷酸肌醇受体 3）。
Arterioscler Thromb Vasc Biol. 2019 May;39(5):902-914. doi: 10.1161/ATVBAHA.118.312301.
6
PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools.PANTHER 版本 14：更多基因组、一个新的 PANTHER GO-slim 和富集分析工具的改进。
Nucleic Acids Res. 2019 Jan 8;47(D1):D419-D426. doi: 10.1093/nar/gky1038.
7
Cardiovascular Outcomes After Lower Extremity Endovascular or Surgical Revascularization: The EUCLID Trial.下肢血管腔内或手术血运重建后的心血管结局：EUCLID 试验。
J Am Coll Cardiol. 2018 Oct 2;72(14):1563-1572. doi: 10.1016/j.jacc.2018.07.046.
8
Major Adverse Limb Events and 1-Year Outcomes After Peripheral Artery Revascularization.外周动脉血运重建术后主要肢体不良事件和 1 年结局。
J Am Coll Cardiol. 2018 Aug 28;72(9):999-1011. doi: 10.1016/j.jacc.2018.06.041.
9
Circulating myomiRs: a new class of biomarkers to monitor skeletal muscle in physiology and medicine.循环肌微小 RNA：监测生理学和医学中骨骼肌的新型生物标志物。
J Cachexia Sarcopenia Muscle. 2018 Feb;9(1):20-27. doi: 10.1002/jcsm.12227. Epub 2017 Nov 28.
10
Sortilin and Its Multiple Roles in Cardiovascular and Metabolic Diseases.Sortilin 及其在心血管和代谢疾病中的多种作用。
Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):19-25. doi: 10.1161/ATVBAHA.117.310292. Epub 2017 Nov 30.
Zotero 插件