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阴茎假体植入治疗勃起功能障碍的长期疗效:单中心经验

Long-term outcomes after penile prosthesis placement for the Management of Erectile Dysfunction: a single-Centre experience.

作者信息

Frydman Valentine, Pinar Ugo, Abdessater Maher, Akakpo William, Grande Pietro, Audouin Marie, Mozer Pierre, Chartier-Kastler Emmanuel, Seisen Thomas, Roupret Morgan

机构信息

Department of Urology, Sorbonne Université, GRC n 5, Predictive Onco-Urology, APHP, Hôpital Pitié-Salpêtrière, F-75013, Paris, France.

Department of Urology, Sorbonne Université, APHP, Hôpitaux universitaires Pitié-Salpêtrière-Charles Foix, F-75013, Paris, France.

出版信息

Basic Clin Androl. 2021 Mar 4;31(1):4. doi: 10.1186/s12610-021-00123-x.

DOI:10.1186/s12610-021-00123-x
PMID:33658014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7931532/
Abstract

BACKGROUND

Penile prothesis (PP) is the gold-standard treatment of drug-refractory erectile dysfunction (ED). While postoperative outcomes have been widely described in the literature, there are few data about patient satisfaction and intraoperative events. We aimed to assess long-term patient satisfaction and perioperative outcomes after PP implantation in a single-centre cohort of unselected patients using validated scales.

RESULTS

A total of 130 patients received a PP (median age: 62.5 years [IQR: 58-69]; median International Index of Erectile Function (IEEF-5) score: 6 [IQR: 5-7]). Median follow-up was 6.3 years [IQR: 4-9.4]. Thirty-two (24.6%) patients underwent surgical revision, of which 20 were PP removals (15.4%). Global PP survival rate was 84.6% and previous PP placement was a risk factor for PP removal (p = 0.02). There were six (4.6%) non-life-threatening intraoperative events including two which resulted in non-placement of a PP (1.5%). EAUiaic grade was 0 for 124 procedures (95.4%), 1 for four procedures (3.1%) and 2 for two procedures (1.5%). Of patients who still had their PP at the end of the study, 91 (80.5%) expressed satisfaction.

CONCLUSIONS

PP implantation is a last-resort treatment for ED with a satisfactory outcome. PPs are well accepted by patients.

摘要

背景

阴茎假体(PP)是药物难治性勃起功能障碍(ED)的金标准治疗方法。虽然术后结果在文献中已有广泛描述,但关于患者满意度和术中事件的数据却很少。我们旨在使用经过验证的量表,评估在一个未选择患者的单中心队列中,PP植入术后的长期患者满意度和围手术期结果。

结果

共有130例患者接受了PP植入(中位年龄:62.5岁[四分位间距:58 - 69];国际勃起功能指数(IEEF - 5)中位评分:6[四分位间距:5 - 7])。中位随访时间为6.3年[四分位间距:4 - 9.4]。32例(24.6%)患者接受了手术翻修,其中20例为PP取出(15.4%)。PP的总体生存率为84.6%,既往PP植入是PP取出的一个危险因素(p = 0.02)。有6例(4.6%)非危及生命的术中事件,其中2例导致未植入PP(1.5%)。124例手术(95.4%)的欧洲泌尿外科学会(EAU)阴茎假体植入后并发症分级为0级,4例手术(3.1%)为1级,2例手术(1.5%)为2级。在研究结束时仍保留PP的患者中,91例(80.5%)表示满意。

结论

PP植入是ED的一种最终治疗手段,效果令人满意。PP被患者广泛接受。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a768/7931532/b937e26ccc20/12610_2021_123_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a768/7931532/b937e26ccc20/12610_2021_123_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a768/7931532/b937e26ccc20/12610_2021_123_Fig1_HTML.jpg

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