Health Research Institute, University of Canberra, Canberra, Australia.
Geohealth Laboratory, Dasman Diabetes Institute, Kuwait City, Kuwait.
Br J Nutr. 2022 Jan 14;127(1):92-102. doi: 10.1017/S0007114521000751. Epub 2021 Mar 4.
This study aimed to determine anthropometric cut-points for screening diabetes and the metabolic syndrome (MetS) in Arab and South Asian ethnic groups in Kuwait and to compare the prevalence of the MetS based on the ethnic-specific waist circumference (WC) cut-point and the International Diabetes Federation (IDF) and American Heart Association/National Heart, Lung, and Blood Institute WC criteria. The national population-based survey data set of diabetes and obesity in Kuwait adults aged 18-60 years was analysed. Age-adjusted logistic regression and receiver operating characteristic (ROC) analyses were conducted to evaluate for 3589 individuals the utility of WC, waist:height ratio (WHtR) and BMI to discriminate both diabetes and ≥3 CVD risk factors. Areas under the ROC curve were similar for WC, WHtR and BMI. In Arab men, WC, WHtR and BMI cut-offs for diabetes were 106 cm, 0·55 and 28 kg/m2 and for ≥3 CVD risk factors, 97 cm, 0·55 and 28 kg/m2, respectively. In Arab women, cut-offs for diabetes were 107 cm, 0·65 and 33 kg/m2 and for ≥3 CVD risk factors, 93 cm, 0·60 and 30 kg/m2, respectively. WC cut-offs were higher for South Asian women than men. IDF-based WC cut-offs corresponded to a higher prevalence of the MetS across sex and ethnic groups, compared with Kuwait-specific cut-offs. Any of the assessed anthropometric indices can be used in screening of diabetes and ≥3 CVD risk factors in Kuwaiti Arab and Asian populations. ROC values were similar. The WC threshold for screening the MetS in Kuwaiti Arabs and South Asians is higher for women.
本研究旨在确定针对科威特阿拉伯和南亚族裔人群的糖尿病和代谢综合征（MetS）筛查的人体测量切点，并比较基于特定族裔腰围（WC）切点和国际糖尿病联合会（IDF）及美国心脏协会/国家心肺血液研究所（AHA/NHLBI）WC 标准的 MetS 患病率。分析了科威特成年人（18-60 岁）基于人群的糖尿病和肥胖国家调查数据集。对 3589 名个体进行了年龄校正的逻辑回归和接收者操作特征（ROC）分析，以评估 WC、腰围与身高比（WHtR）和 BMI 对糖尿病和≥3 个心血管疾病（CVD）风险因素的区分能力。ROC 曲线下面积（AUC）对于 WC、WHtR 和 BMI 均相似。在阿拉伯男性中，糖尿病的 WC、WHtR 和 BMI 切点分别为 106cm、0.55 和 28kg/m2，≥3 个 CVD 风险因素的切点分别为 97cm、0.55 和 28kg/m2。在阿拉伯女性中，糖尿病的 WC、WHtR 和 BMI 切点分别为 107cm、0.65 和 33kg/m2，≥3 个 CVD 风险因素的切点分别为 93cm、0.60 和 30kg/m2。南亚女性的 WC 切点高于男性。与科威特特定切点相比，基于 IDF 的 WC 切点对应于更大的性别和族裔群体中 MetS 的患病率。任何评估的人体测量指数都可用于筛查科威特阿拉伯和亚洲人群的糖尿病和≥3 个 CVD 风险因素。ROC 值相似。科威特阿拉伯人和南亚人筛查 MetS 的 WC 阈值女性更高。
