Pediatrics, All India Institute of Medical Sciences, Patna, India
Pediatrics, All India Institute of Medical Sciences, Patna, India.
BMJ Case Rep. 2021 Mar 3;14(3):e241087. doi: 10.1136/bcr-2020-241087.
Asymptomatic individuals positive for SARS-CoV-2 RNA constitute a significant proportion of the infected population and play a role in the transmission of the virus. We describe a healthcare worker who presented with fever and malaise and was diagnosed with mild COVID-19. The symptoms resolved within 4 days but there was persistent positivity of viral RNA in the upper respiratory tract for more than 58 days, which is the longest reported duration of persistence of SARS-CoV-2 in a healthcare worker. In this case report, we discuss clinical and administrative issues such as the role of asymptomatic cases in the transmission of the virus to patients and coworkers as an occupational hazard, interpretation of persistent positivity of nucleic acid test, duration of isolation and return-to-work guidelines pertinent to researchers and global health policymakers.
无症状的 SARS-CoV-2 RNA 阳性个体在感染人群中占很大比例，并在病毒传播中发挥作用。我们描述了一位出现发热和不适症状并被诊断为轻度 COVID-19 的医护人员。症状在 4 天内得到缓解，但上呼吸道的病毒 RNA 持续阳性超过 58 天，这是报告的医护人员中 SARS-CoV-2 持续时间最长的一次。在本病例报告中，我们讨论了临床和管理方面的问题，如无症状病例作为职业危害向患者和同事传播病毒的作用、核酸检测持续阳性的解释、隔离和重返工作岗位指南的持续时间与研究人员和全球卫生政策制定者相关。
