Jędrzejek Michał Jacek, Mastalerz-Migas Agnieszka, Janicka Paulina
Department of Family Medicine, Wroclaw Medical University, W. Syrokomli 1, 51-141 Wroclaw, Poland.
Department of Pathology, Wroclaw University of Environmental and Life Sciences, Norwida 31, 50-375 Wroclaw, Poland.
Int J Environ Res Public Health. 2022 Mar 8;19(6):3159. doi: 10.3390/ijerph19063159.
Background: Healthcare workers (HCWs) are more exposed to influenza infection, and the influenza vaccination is recommended each year, to reduce the risk of influenza infection and prevent influenza transmission. This study is a cross-sectional study and the objectives were to determine the rate of influenza virus infection among HCWs in the 2019−2020 influenza season. Methods: Between January and March 2020, a survey was carried out in 2 hospitals and 15 primary health-care settings (PHCS) in Wroclaw (Poland). The novel point-of-care testing Flu SensDx device was used, which detects the M1 protein of the influenza virus using electrochemical impedance spectroscopy from biological material (throat/nasal swabs). Results: A total of 150 samples were collected. The majority of participating HCWs by profession were 83 physicians (55.3%) and half (51.3%) of the participating HCWs worked in PHCS. Influenza vaccination coverage was 61.3% in 2019−2020 and 46.0% in the 2018−2019 season for all participants. Of the participating HCWs, 44.0% were positive tested by the Flu SensDx device. There were no statistically significant differences among the positive tested HCWs, their influenza immunization history, and the presence of symptoms of influenza-like illness (p > 0.05). Conclusion: Although the results of the present study suggest that influenza vaccination does not reduce the frequency of influenza virus detection by Flu SensDx testing in the HCWs participants, larger studies are needed to estimate the incidence of influenza virus infection among HCWs to understand the underlying mechanism and fine-tune policies aimed at reducing nosocomial infections.
医护人员更容易感染流感，建议每年接种流感疫苗，以降低感染流感的风险并防止流感传播。本研究为横断面研究，目的是确定2019 - 2020流感季节医护人员中流感病毒感染率。方法：2020年1月至3月，在弗罗茨瓦夫（波兰）的2家医院和15个初级卫生保健机构（PHCS）进行了一项调查。使用了新型即时检测流感传感诊断设备，该设备通过电化学阻抗谱从生物材料（咽喉/鼻拭子）中检测流感病毒的M1蛋白。结果：共收集了150份样本。参与调查的医护人员中，大多数为83名医生（55.3%），一半（51.3%）的参与医护人员在初级卫生保健机构工作。所有参与者的流感疫苗接种覆盖率在2019 - 2020年为61.3%，在2018 - 2019季节为46.0%。在参与调查的医护人员中，44.0%通过流感传感诊断设备检测呈阳性。检测呈阳性的医护人员、他们的流感免疫史以及流感样疾病症状的出现情况之间没有统计学上的显著差异（p>0.05）。结论：尽管本研究结果表明，流感疫苗接种并未降低参与调查的医护人员中通过流感传感诊断检测出流感病毒的频率，但需要更大规模的研究来估计医护人员中流感病毒感染的发生率，以了解其潜在机制并微调旨在减少医院感染的政策。
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