Neumann Melissa, Quintero Javier, Shih Tiffany, Capitle Eugenio M
Internal Medicine, Rutgers University, Newark, USA.
Rheumatology, Rutgers University, Newark, USA.
Cureus. 2021 Jan 29;13(1):e12996. doi: 10.7759/cureus.12996.
Symptoms of dry eyes or dry mouth, otherwise known as sicca symptoms, are not always present in patients with Sjögren's syndrome (SS). Approximately 20% of patients with SS do not have sicca symptoms. An unusual case of a patient presenting with complete left-sided facial hemiparesis, a history of partial bilateral sensorineural hearing loss who was found to have elevated antinuclear antibody (ANA) with high titer positive SSA/Ro antibody, evidence of bilateral parotitis on imaging and absence of sicca symptoms, prompted us to perform a literature review. Twelve case reports relating facial nerve palsy and Sjögren's were found and only one described a similar constellation of features of unilateral facial weakness and otalgia. Management of facial nerve palsy related to Sjögren's is unclear but pharmacological agents have included corticosteroids, intravenous immune globulin (IVIG), cyclophosphamide, and plasmapheresis. This case report describes a patient whose facial nerve palsy is attributed to SS, explores peripheral and central nervous system involvement in SS, and provides some recommended treatments.
干眼症或口干症的症状,也被称为干燥症状,并不总是出现在干燥综合征(SS)患者身上。约20%的SS患者没有干燥症状。有这样一例不寻常的病例,一名患者出现左侧完全性面部偏瘫,有双侧部分感音神经性听力损失病史,抗核抗体(ANA)升高且SSA/Ro抗体高滴度阳性,影像学检查显示双侧腮腺炎,且无干燥症状,这促使我们进行了文献综述。我们发现了12例关于面神经麻痹与干燥综合征的病例报告,其中只有1例描述了类似的单侧面部无力和耳痛特征组合。与干燥综合征相关的面神经麻痹的治疗方法尚不清楚,但药物治疗包括皮质类固醇、静脉注射免疫球蛋白(IVIG)、环磷酰胺和血浆置换。本病例报告描述了一名面神经麻痹归因于干燥综合征的患者,探讨了干燥综合征患者外周和中枢神经系统受累情况,并提供了一些推荐的治疗方法。