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大希腊经导管主动脉瓣植入登记处:关于造影剂渗透压和术后急性肾损伤的数据

Magna Graecia transcatheter aortic valve implantation registry: data on contrast medium osmolality and postprocedural acute kidney injury.

作者信息

Iacovelli Fortunato, Pignatelli Antonio, Cafaro Alessandro, Stabile Eugenio, Salemme Luigi, Cioppa Angelo, Pucciarelli Armando, Spione Francesco, Loizzi Francesco, De Cillis Emanuela, Pestrichella Vincenzo, Bortone Alessandro Santo, Tesorio Tullio, Contegiacomo Gaetano

机构信息

Division of University Cardiology, Cardiothoracic Department, Policlinico University Hospital, Piazza Giulio Cesare 11, 70124 Bari, Italy.

Interventional Cardiology Service, "Anthea" Clinic, GVM Care & Research, Bari, Italy.

出版信息

Data Brief. 2021 Feb 2;35:106827. doi: 10.1016/j.dib.2021.106827. eCollection 2021 Apr.

DOI:10.1016/j.dib.2021.106827
PMID:33659591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7890109/
Abstract

A comprehensive description of baseline characteristics, procedural features and outcomes related to the development of acute kidney injury (AKI) after transcatheter aortic valve implantation (TAVI) is reported in our research paper (). Three Italian heart centers were involved in this multicentric observational study. Between March 2011 and February 2019, a total of 888 patients underwent TAVI; according to the inclusion and exclusion criteria, 697 patients were included in the post-hoc analysis. This Data in Brief paper aims to report demographic, clinical, laboratory, echocardiographic, intraprocedural, periprocedural, postprocedural and follow-up data; all of them were prospectively collected from each patient's health record, whereas the analysis was performed retrospectively. Targets of this data analysis were: 1) to evaluate the impact of contrast medium (CM) osmolality on TAVI-related AKI; 2) to identify the most of risk factors involved in the development of such complication, and consequently in the occurrence of 1-year mortality; 3) to estimate the impact of CM osmolality on AKI in specific patient subgroups.

摘要

我们的研究论文()报道了经导管主动脉瓣植入术(TAVI)后与急性肾损伤(AKI)发生相关的基线特征、手术特征和结果的全面描述。三个意大利心脏中心参与了这项多中心观察性研究。2011年3月至2019年2月期间,共有888例患者接受了TAVI;根据纳入和排除标准,697例患者被纳入事后分析。本数据简报旨在报告人口统计学、临床、实验室、超声心动图、术中、围手术期、术后和随访数据;所有这些数据均前瞻性地从每位患者的健康记录中收集,而分析是回顾性进行的。该数据分析的目标是:1)评估造影剂(CM)渗透压对TAVI相关AKI的影响;2)识别此类并发症发生以及因此导致1年死亡率发生的主要危险因素;3)估计CM渗透压对特定患者亚组中AKI的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dc8/7890109/eafc66f46244/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dc8/7890109/93234085cf74/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dc8/7890109/40e6c5f8f679/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dc8/7890109/eafc66f46244/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dc8/7890109/93234085cf74/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dc8/7890109/40e6c5f8f679/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dc8/7890109/eafc66f46244/gr3.jpg

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本文引用的文献

1
Impact of contrast medium osmolality on the risk of acute kidney injury after transcatheter aortic valve implantation: insights from the Magna Graecia TAVI registry.经导管主动脉瓣植入术后对比剂渗透压对急性肾损伤风险的影响:来自 Magna Graecia TAVI 注册研究的见解。
Int J Cardiol. 2021 Apr 15;329:56-62. doi: 10.1016/j.ijcard.2020.12.049. Epub 2020 Dec 25.
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Application of student's -test, analysis of variance, and covariance.学生 t 检验、方差分析和协方差分析的应用。
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Modified Wilcoxon-Mann-Whitney Test and Power against Strong Null.
修正的威尔科克森-曼-惠特尼检验及针对强原假设的检验功效
Am Stat. 2019;73(1):43-49. doi: 10.1080/00031305.2017.1328375. Epub 2018 May 10.
4
The ratio of contrast volume to glomerular filtration rate predicts acute kidney injury and mortality after transcatheter aortic valve implantation.对比剂用量与肾小球滤过率的比值可预测经导管主动脉瓣植入术后的急性肾损伤和死亡率。
Cardiovasc Revasc Med. 2017 Jul-Aug;18(5):349-355. doi: 10.1016/j.carrev.2017.02.011. Epub 2017 Feb 20.
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The importance of contrast volume/glomerular filtration rate ratio in contrast-induced nephropathy patients after transcatheter aortic valve implantation.经导管主动脉瓣植入术后对比剂肾病患者对比剂体积/肾小球滤过率比值的重要性。
Cardiorenal Med. 2015 Feb;5(1):31-9. doi: 10.1159/000369943. Epub 2014 Dec 20.
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The potential for increased power from combining P-values testing the same hypothesis.合并检验相同假设的P值来提高检验效能的可能性。
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