氟康唑单药治疗真菌性人工膝关节感染的一期翻修术
Single-Stage Revision With Fluconazole Monotherapy in Fungal Prosthetic Knee Joint Infections.
作者信息
George James C, Sainulabdeen Jishar, Chittaranjan Samuel, George Koshy, Babu Subin
机构信息
Department of Orthopaedics, Believer's Church Medical College and Hospital, Thiruvalla, Kerala, India.
出版信息
Arthroplast Today. 2021 Feb 11;7:238-241. doi: 10.1016/j.artd.2020.12.014. eCollection 2021 Feb.
Abstract
Fungal prosthetic joint infection is rare, and two-stage revision is usually advocated. We present our experience with 2 cases of fungal prosthetic knee joint infection presenting 25 months and 3 years after index surgery. Both patients were managed with single-stage revision arthroplasty and fluconazole monotherapy. They remain asymptomatic with good knee society score after 2 years of follow-up. Preoperative workup of all aseptic loosening cases should include extended culture for fungal elements. Single-stage revision with antifungal therapy for 3 months gives good results in nonimmunocompromised patients with good soft-tissue envelope.
摘要
真菌性人工关节感染较为罕见，通常主张进行两阶段翻修。我们介绍了2例人工膝关节真菌性感染的经验，这2例患者分别在初次手术后25个月和3年出现感染。两名患者均接受了单阶段翻修关节成形术和氟康唑单一疗法。经过2年的随访，他们均无症状，膝关节协会评分良好。所有无菌性松动病例的术前检查应包括真菌成分的延长培养。对于软组织包膜良好的非免疫受损患者，单阶段翻修并进行3个月的抗真菌治疗可取得良好效果。
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